Nonvenereal Treponematoses

  • Sabine Enenkel
  • Wolfgang Stille


The treatment schedule laid down by the WHO Scientific Group on Treponemal Infections in 1980 [5] applies to all of the three nonvenereal treponematoses, yaws, endemic syphilis, and pinta (Table 31.1). Doses of benzathine penicillin higher than those suggested by WHO were used in the antiyaws campaign in Ghana. Adults received 2.4 megaunits (MU), children less 15 years old were given 1.2 MU and those less than 6 years old received 0.3 MU [1].


Treatment Schedule Active Case African Region Scientific Group Mass Treatment 
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  1. 1.
    Agadzi VK, Aboagye-Atta Y, Nelson JW, Perine PL, Hopkins DR (1983) Resurgence of yaws in Ghana. Lancet II: 389–390CrossRefGoogle Scholar
  2. 2.
    Brown ST (1985) Therapy for nonvenereal treponematoses: review of the efficacy of penicillin and consideration of alternatives. Rev Infect Dis 7 [Suppl 2]: S318–S326PubMedCrossRefGoogle Scholar
  3. 3.
    Garner PA, Talwat EN, Hill G, Reid MS, Garner MF (1986) Yaws reappears. Papua New Guinea Med J 29: 247–252Google Scholar
  4. 4.
    Widy-Wirski R (1985) Surveillance and control of resurgent yaws in the African region. Rev Infect Dis 7 [Suppl 2]: S227–S232CrossRefGoogle Scholar
  5. 5.
    WHO Scientific Group (1982) Treponemal infections. Tech Rep Ser No 674. WHO, GenevaGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • Sabine Enenkel
    • 1
  • Wolfgang Stille
    • 2
  1. 1.Department of PediatricsUniversity Hospital, Johann Wolfgang Goethe-UniversitätFrankfurt/Main 70Germany
  2. 2.Department of Internal MedicineUniversity Hospital Johann Wolfgang Goethe-UniversitätFrankfurt/Main 70Germany

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