Melioidosis is a rare disease that is endemic in Southeast Asia, where the causative agent, Pseudomonas pseudomallei, is widely distributed in soil. Most cases have been reported from Vietnam, Malaysia, Burma, and Thailand, but the disease occurs worldwide between latitudes 20° north and 20° south. Subclinical infection is not rare, as indicated by serological surveys, and delayed reactivation may occur after years of latency.
KeywordsMethylene Blue Subclinical Infection Serological Survey Body Secretion Quinolone Derivative
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