Cholinesterases: Tissue and Cellular Distribution of Molecular Forms and Their Physiological Regulation

  • J.-P. Toutant
  • J. Massoulié
Part of the Handbook of Experimental Pharmacology book series (HEP, volume 86)


In Chapter 8 a we have described the molecular structure and the interactions of the multiple molecular forms of acetylcholinesterase (AChE, EC and butyrylcholinesterase (BuChE, EC in vertebrates. We show there that the two enzymes present globular forms (G1 G2, G4) which exist as non-hydrophobic as well as amphiphilic molecules, and asymmetric, collagen-tailed molecules (A4, A8, A12). These molecular forms may be further subdivided according to the binding of lectins or according to their electrophoretic migrations in nondenaturing electrophoresis.


AChE Activity Molecular Form Asymmetric Form Globular Form Mouse Muscle Cell 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • J.-P. Toutant
  • J. Massoulié

There are no affiliations available

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