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Molecular Basis of Viral and Microbial Pathogenesis pp 39–50Cite as

Virus Genes Involved in Host Range and Pathogenicity

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Abstract

The pathogenicity of a virus should always be considered in relation to its host, the organ or the individual cell in which it multiplies. During the infectious cycle, viral proteins have to cooperate with each other and have to interact with cellular components at the right time, in the correct sequence, in order to enable the virus to replicate. These cooperations and interactions can be influenced by mutations, or recombination of viral genes in the sense that pathogenic properties of a virus might be lost or created. By correlating specific changes of viral structures with such biological phenotypes, general molecular mechanisms related to pathogenicity can be studied and, when understood, may eventually be used to overcome the virus disease.

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Author information

Authors and Affiliations

  1. Institut für Virologie, Justus-Liebig-Universität Giessen, Frankfurter Straße 107, D-6300, Giessen, Germany

    C. Scholtissek

Authors
  1. C. Scholtissek
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Editor information

Editors and Affiliations

  1. Institut für Virologie der Universität, Frankfurter Straße 107, 6300, Gießen, Germany

    Rudolf Rott

  2. Institut für Genetik und Mikrobiologie der Universität, Röntgenring 11, 8700, Würzburg, Germany

    Werner Goebel

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© 1987 Springer-Verlag Berlin Heidelberg

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Scholtissek, C. (1987). Virus Genes Involved in Host Range and Pathogenicity. In: Rott, R., Goebel, W. (eds) Molecular Basis of Viral and Microbial Pathogenesis. Colloquium der Gesellschaft für Biologische Chemie 9.–11. April 1987 in Mosbach/Baden, vol 38. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73214-0_4

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  • DOI: https://doi.org/10.1007/978-3-642-73214-0_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-73216-4

  • Online ISBN: 978-3-642-73214-0

  • eBook Packages: Springer Book Archive

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