Effects of Phorbol Esters on Membrane Currents and Synaptic Efficacy in the Hippocampus

Madison, D. V.; Malenka, R. C.; Nicoll, R. A.

doi:10.1007/978-3-642-73202-7_33

D. V. Madison³^nAff4,
R. C. Malenka³ &
R. A. Nicoll³

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Abstract

Application of phorbol esters to hippocampal slices has been shown to enhance synaptic transmission in a way that mimics long term potentiation. These compounds also have effects on a voltage-dependent chloride current that could possibly account for some aspects of this potentiating action.

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D. V. Madison
Present address: Department of Physiology, Yale School of Medicine, 06510, New Haven, CT, USA

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Departments of Pharmacology and Physiology, University of California, 94143, San Francisco, CA, USA
D. V. Madison, R. C. Malenka & R. A. Nicoll

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D. V. Madison
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R. C. Malenka
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R. A. Nicoll
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Editors and Affiliations

II. Physiologisches Institut, Johannes Gutenberg-Universität, Saarstrasse 21, 6500, Mainz, Germany
Helmut L. Haas M.D.
Department of Neurosciences MO24, University of California at San Diego, 92093, La Jolla, CA, USA
György Buzsàki M.D.

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Madison, D.V., Malenka, R.C., Nicoll, R.A. (1988). Effects of Phorbol Esters on Membrane Currents and Synaptic Efficacy in the Hippocampus. In: Haas, H.L., Buzsàki, G. (eds) Synaptic Plasticity in the Hippocampus. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73202-7_33

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DOI: https://doi.org/10.1007/978-3-642-73202-7_33
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-73204-1
Online ISBN: 978-3-642-73202-7
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