Long-Term Potentiation in Slices from Human Hippocampus
Long-term potentiation (LTP) has been observed in slices from human hippocampi removed for intractable epilepsy using extra- and intracellular recording in vitro. Furthermore the effects of several neuroactive substances with possible relevance for synaptic plasticity was investigated. Human hippocampal neurones in vitro display properties very similar to the respective rodent cells.
KeywordsTemporal Lobe Epilepsy Intracellular Recording Population Spike Synaptic Potential Perfusion Chamber
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