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Potassium Channels in Rat Brain Synaptosomes: Pharmacology and Toxicology

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Cellular and Molecular Basis of Synaptic Transmission

Part of the book series: NATO ASI Series ((ASIH,volume 21))

Abstract

Potassium channels appear to be the most diverse group of ion channels in biological systems (Hille, 1984; Yellen, 1987). Neuronal K channels play key roles in the control of membrane potential, action potential repolarization, repetitive firing, and higher functions such as learning and memory. However, relatively little is known about the properties of K channels in presynaptic nerve terminals because these channels are difficult to study with traditional electrophysiological methods. This is a significant gap in our knowledge because these nerve terminal K channels may play a critical role in the control of synaptic transmission.

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Author information

Author notes

  1. Christina G. Benishin

    Present address: Department of Physiology, University of Alberta Faculty of Medicine, Edmonton, Alberta, Canada, T6G 2H7

Authors and Affiliations

  1. Department of Physiology, University of Maryland School of Medicine, 655 West Baltimore Street, Baltimore, Maryland, 21201, USA

    Mordecai P. Blaustein, Dieter K. Bartschat, Christina G. Benishin, Kathryn A. Colby, Bruce K. Krueger, Mary J. Schneider & Roger G. Sorensen

  2. Department of Biological Sciences, Carnegie-Mellon University, 4400 Fifth Avenue, Pittsburgh, Pennsylvania, 15213, USA

    William E. Brown

Authors
  1. Mordecai P. Blaustein
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  2. Dieter K. Bartschat
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  3. Christina G. Benishin
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  4. William E. Brown
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  5. Kathryn A. Colby
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  6. Bruce K. Krueger
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  7. Mary J. Schneider
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  8. Roger G. Sorensen
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Editor information

Editors and Affiliations

  1. AK Neurochemie, Zoologisches Institut der J. W. Goethe-Universität, Siesmayerstraße 70, 6000, Frankfurt am Main, Germany

    Herbert Zimmermann

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© 1988 Springer-Verlag Berlin Heidelberg

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Blaustein, M.P. et al. (1988). Potassium Channels in Rat Brain Synaptosomes: Pharmacology and Toxicology. In: Zimmermann, H. (eds) Cellular and Molecular Basis of Synaptic Transmission. NATO ASI Series, vol 21. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73172-3_15

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  • DOI: https://doi.org/10.1007/978-3-642-73172-3_15

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-73174-7

  • Online ISBN: 978-3-642-73172-3

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