Gaba and Taurine as Signals for Neuronal Development and Differentiation

  • Arne Schousboe
  • Gert H. Hansen
  • Bo Belhage
  • Jens H. Abraham
  • Eddi Meier
Conference paper
Part of the NATO ASI Series book series (volume 22)


During recent years evidence has been accumulating that different classical neurotransmitters such as serotonin, catecholamines and the amino acids GABA and taurine may serve as epigenetic factors during neuronal development and differentiation (Lauder,1983; Haydon et al.,1984; Konig et al., 1986; Redburn & Schousboe,1987). Since a variety of macromo- lecular compounds, mainly peptides, are also known to act as neurotrophic factors (Manthorpe et al., 1986) it is clear that the extremely complex processes which govern the development and differentiation of the neuronal network and communication system in the central nerve system are subject to regulation at a number of different levels. The present review will concentrate on a summary of the recent progress in studies concerned with the possible role of GABA and taurine as agents stimulating neuronal development.


Gaba Receptor Cerebellar Granule Cell Gaba Agonist Neurotrophic Activity Gaba Binding 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • Arne Schousboe
    • 1
  • Gert H. Hansen
    • 1
  • Bo Belhage
    • 1
  • Jens H. Abraham
    • 1
  • Eddi Meier
    • 1
  1. 1.Department of Biochemistry A, Panum InstituteUniversity of CopenhagenCopenhagen NDenmark

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