Renal Function in Lithium Treatment

  • C. Bismuth
  • F. J. Baud
  • M. Godin
Part of the Archives of Toxicology book series (TOXICOLOGY, volume 12)


Proposed since the 1950s in the treatment of chronic manic psychosis, lithium has a well-documented neurological and digestive toxicity. It also can induce a nephrogenic diabetes insipidus. Whether or not lithium is capable of inducing morphological renal damage in mammals remains a topic of debate:
  1. 1.

    An experimental study has recently stated that lithium could be proposed in a model for regularly producing interstitial nephritis in rabbit (Walker et al. 1986).

  2. 2.

    Renal toxicity in man is denied by Schou (1986), the promoter of lithium therapy.



Interstitial Nephritis Lithium Treatment Acute Pyelonephritis Nephrogenic Diabetes Insipidus Lithium Therapy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag 1988

Authors and Affiliations

  • C. Bismuth
    • 1
  • F. J. Baud
    • 1
  • M. Godin
    • 2
  1. 1.Clinique ToxicologiqueHôpital Fernand WidalParisFrance
  2. 2.Centre Hospitalier Régional et Universitaire de RouenHôpital de BoisguillaumeBoisguillaume CedexFrance

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