Abstract
Today’s routine therapy of insulin-dependent diabetes mellitus (IDDM) is a good example of how treatment of symptoms may help the patient stay alive without curing him. The discovery of insulin by Banting and Best in 1922 and its introduction in clinical therapy lowered early diabetes lethality dramatically. Despite many attempts however, a prevention of late diabetic complications and of their contribution to common morbidity and lethality has not yet been achieved [1]. A major point of any therapy of diabetes remains whether the late-diabetic syndrome can be cured or prevented. Total endocrine-replacement therapy seems a promising attempt toward reaching this goal [2, 3]. Nevertheless, before its becoming a routine therapy many problems must be solved. Therefore, grafting either of the whole pancreas or of isolated islets of Langerhans and the related problems remain an important matter for experimental research.
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© 1987 Springer Verlag Berlin Heidelberg
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von Specht, B.U., Dibelius, A., Königsberger, H. (1987). New Treatment Concepts for Insulin-Dependent Diabetes Mellitus. In: Baethmann, A., Messmer, K. (eds) Surgical Research: Recent Concepts and Results. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73097-9_11
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DOI: https://doi.org/10.1007/978-3-642-73097-9_11
Publisher Name: Springer, Berlin, Heidelberg
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