What is the action of sucralfate in the treatment of peptic esophagitis?

  • S. Bonfils
  • M. Dubrasquet
  • J. P. Galmiche
  • D. Cloarec
Conference paper

Abstract

Sucralfate is a basic saccharose sulfate of aluminium whose mode of action should prove of therapeutic value in reflux esophagitis with ulcerated lesions. It has been shown that this agent forms a complex with the proteins exposed by ulcerated gastric lesions, thereby adhering locally and constituting an effective barrier to the aggressive action of acid, pepsin and bile-salts.

Keywords

Placebo Permeability Saccharose Albumin Alginate 

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References

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Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • S. Bonfils
    • 1
    • 2
  • M. Dubrasquet
    • 1
  • J. P. Galmiche
    • 2
  • D. Cloarec
    • 2
  1. 1.ParisFrance
  2. 2.Nantes, ParisFrance

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