Does the symptomatology of cancer differ when occurring in Barrett’s esophagus?
In order to answer this question, the clinical characteristics of adenocarcinoma arising in Barrett’s esophagus must be defined (Table 1). Patients with such adenocarcinoma generally have an average age of 61 years. Barrett’s esophagus is predominantly a disease of white males, and I have been unable to find a single case report of esophageal adenocarcinoma in a black patient. This is a striking contrast to the predominance of black males among patients with squamous cell carcinoma of the esophagus. The male to female ratio in patients with adenocarcinoma in Barrett’s esophagus is about 4–5 to 1.
- 2.Haggitt RC, Dean PJ (1985) Adenoeareinoma in Barrett’s epithelium. Chapter 14 in Barrett’s Esophagus — Pathophysiology, Diagnosis, and Management. Speehler SJ, Goyal RK (eds) Elsevier Seienee Publishing Co, NewYork, pp 153–165Google Scholar