How long does it take for Barrett’s esophagus to develop?
Barrett’s columnar-hned esophagus (CLE) is the result of a creeping substitution of reflux denuded squamous epithehum by columnar epithehum which is derived from the gastric fundic epithehum. Experimental and chnical evidence has shown that the replacement process is a very slow one. The process is one of repair, and the denuded segment is the stimulus for replacement by acid-resistent columnar epithelium
KeywordsSquamous Epithelium Clin Pathol Columnar Epithelium Reflux Episode Esophageal Acid Exposure
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- 1.Bremner CG, Lynch VP, Ellis FH Jr (1970) Barrett’s esophagus: Congenital or Acquired? An experimental study of mucosal regeneration in the dog Surgery 68(1): 209–216Google Scholar
- 3.Pollaro W (1982) An experimental study of mucosal regeneration in Barrett’s esophagus. Thesis presented to University of Sao Paulo BrazilGoogle Scholar
- 7.Goldman MC and Beckmann RC (1960) Barrett Syndrome. Case report with discussion about concepts and pathogenesis. Gastroenterol 39:104–110Google Scholar
- 4.Savary M, Monnier P (1985) Diagnosis, pathophysiology, and adenocarcinogenesis of Barrett’s esophagus. Esophageal disorders: pathophysiology, and therapy, edited by DeMeester TR, Skinner DB, Raven Press, New YorkGoogle Scholar