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Does the persistence of histologic signs suggest that other factors than acidity could occur?

  • Ch. Fontolliet
  • D. Gardiol
  • Ph. Monnier
  • J. B. Ollyo
  • M. Savary
Conference paper

Abstract

Various histologic features have been described in connection with reflux esophagitis. In particular, these include hyperplasia of the basal layer, elongation of the vascular connective tissue papihae, infiltration of the lamina propria by lympho-plasmocytes [3] or by neutrophil and/or eosinophil granulocytes [8, 9, 12] and vascular changes [1,4].

Keywords

Gastroesophageal Reflux Lamina Propria Reflux Esophagitis Columnar Epithelium Hiatal Hernia Repair 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Geboes K, Desmet V, Vantrappen G, Mebis J (1980) Vascular changes in the esophageal mucosa. An early histologic sign of esophagitis. Gastrointest Endosc 26:29–32PubMedCrossRefGoogle Scholar
  2. 2.
    Hendrix TR, Varoley JH (1976) Consequences of gastroesophageal reflux. Clin Gastroenterol 5:156–174Google Scholar
  3. 3.
    Ismail-Beigi F, Horton PF, Pope CE (1970) Histological consequences of gastroesophageal reflux in man. Gastroenterology 58:163–174PubMedGoogle Scholar
  4. 4.
    Kobayashi S, Kasugai T (1974) Endoscopic and biopsy criteria for the diagnosis of esophagitis with a fibreoptic esophagoscope. Dig Dis 19:345–352CrossRefGoogle Scholar
  5. 5.
    Meier RF, Sieber R, Bauerfeind P, Blum AL (1986) Endoscopy as final arbiter in controlled chnical trials in peptic disorders. Clin Gastroenterol 15:377–391PubMedGoogle Scholar
  6. 6.
    Monnier P, Savary M (1984) Contribution of endoscopy to gastroesophageal reflux disease. Scand J gastroenterol 19: Suppl 106:28–45Google Scholar
  7. 7.
    Savary M, Monnier P (1980) Le reflux gastro-oesophagien: l’apport de l’endoscopie dans l’indication opératoire et les contrôles postopératoires. Helv Chir Acta 47:693–706Google Scholar
  8. 8.
    Seefeld U, Krejs GI, Siebenmann RE, Blum AM (1977) Esophageal histology in gastroesophageal reflux. Morphometries findings in succion biopsies. Am J Dig Dis 22:956–964PubMedCrossRefGoogle Scholar
  9. 9.
    Sonnenberg A, Lepsien G, Muller-Lissner SA, Koelz HR, Siewert JR, Blum AL (1982) When is esophagitis healed? Esophageal endoscopy, histology and function before and after cimetidine treatment. Dig Dis Sci 27:297–302PubMedCrossRefGoogle Scholar
  10. 10.
    Tumala V, Barwick KW, Sontag SJ, Vlahcevic RB, McCallum RW (1987) The significance of intraepithehal eosinophils in the histologic diagnosis of gastroesophageal reflux. Am J Chn Pathol 87:43–48Google Scholar
  11. 11.
    Weinstein WM, Bogoch ER, Bowes KL (1975) The normal human esophageal mucosa: a histological reappraisal. Gastroenterology 68:40–44PubMedGoogle Scholar
  12. 12.
    Winter HS, Madara JL, Stafford RJ (1982) Intraepithehal eosinophihs: a new diagnostic criterion for reflux esophagitis. Gastroenterology 83:818–823PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • Ch. Fontolliet
    • 1
  • D. Gardiol
    • 1
  • Ph. Monnier
    • 1
  • J. B. Ollyo
    • 1
  • M. Savary
    • 1
  1. 1.LausanneSwitzerland

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