Abstract
if we can culture plant cells which produce many medicinal substances in large-scale cultivation, such as bacteria, yeast and mold, we can efficiently obtain many useful complex compounds from simple substances without restricting the natural conditions that affect agricultural production.
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References
Azechi S (1983a) Morphology of tobacco cells in continuous culture. Sci Pap Odawara Salt Exp Stn. Jpn Tobacco Salt Publ Corp 19:103–120.
Azechi S (1983b) Comparison of characteristics in the various culture operation. Jpn Tobacco Salt Publ Corp 19:139–162.
Azechi S, Hashimoto T, Nagatuska S, Yuyama T, Nishiyama T, Murata A, Nakashizuka M (1983a) Continuous culture of tobacco plant cells, pt 1. Growth inhibition in the continuous culture and its solution method. Jpn Tobacco Salt Publ Corp 19:93–101.
Azechi S, Hashimoto T, Nagatuska S, Yuyama T, Nishiyama T, Murata A, Ishii H, Nakashizuka M (1983b) Continuous culture of tobacco plant cells, pt 2. Stability of cell appearance in the continuous culture. Jpn Tobacco Salt Publ Corp 19:103–120.
Azechi S, Hashimoto T, Yuyama T, Nagatuska S, Nakashizuka M, Nishiyama T, Murata A (1983c) Continuous cultivation of tobacco plant cells in an industrial scale plant. Hakkokogaku 61:117–128.
Azechi S, Hashimoto T, Murata A, Miyakita I, Ishii H (1985a) Dynamic measurement of volumetric oxygen transfer coefficient. Jpn Tobacco Salt Publ Corp 20:73–85.
Azechi S, Hashimoto T, Nakashizuka M, Murata A, Ishii H (1985b) Batch culture of tobacco plant cells in high concentration medium. Jpn Tobacco Salt Publ Corp 20:61–71.
Fowler MW (1977) Growth of cell cultures under chemostat conditions. In: Barz W, Reinhard E, Zenk MH (eds) Plant tissue culture and its bio-technological application. Springer, Berlin Heidelberg New York, pp 253–265.
Fujita Y (1985) Production of plant pigments by plant tissue and cell culture. J Synth Org Chem 43:1003–1012.
Fujita Y, Tabata M, Nishi A, Yamada Y (1982) New medium and production of secondary compounds with the two-staged culture method. In: Fujiwara A (ed) Plant tissue culture 1982. Maruzen Tokyo, pp 399–400.
Hashimoto T, Azechi S, Sugita S, Suzuki K (1982) Large-scale production of tobacco cells by continuous cultivation. In: Fujiwara A (ed) Plant tissue culture 1982. Maruzen, Tokyo, pp 403–404.
Hashimoto T, Yuyama T, Nagatuska S, Nakashizuka M, Nishiyama T, Murata A, Azechi S, Suzuki K (1985) Batch culture of tobacco plant cells by large and small fermentors. Sci Pap Odawara Salt Exp Stn. Jpn Tobacco Salt Publ Corp 20:45–59.
Hattori K, Kunihiro H, Yokoo S (1972) Studies on the efficiency of PVA air sterilization filter for collecting airborne microbes. J Ferment Technol 50:432–437.
Iijima M, Kawazoe S, Asakura A, Soh Y (1980) Productivity of tobacco cells in continuous and semicontinuous culture. Sci Pap Centr Res Inst. Jpn Tobacco Salt Publ Corp 122:1–11.
Kato A, Shimizu Y, Nagai S (1975) Biomass production of tobacco cells (1). Effect of initial kLa on the growth of tobacco cells in batch culture. J Ferment Technol 53:744–751.
Kato A, Hashimoto Y, Soh Y (1976a) Effect of temperature on the growth of tobacco cells. J Ferment Technol 54:754–757.
Kato A, Kawazoe S, Iijima M, Shimizu Y (1976b) Biomass production of tobacco cells (II). Continuous culture of tobacco cells. J Ferment Technol 54:82–87.
Kato A, Hukazawa Y, Shimizu Y, So Y, Nagai S (1977) Biomass production of tobacco cells (III). Requirement of PO3− 4, SO2− 4, K+ and Ca2+ for the growth of tobacco cells in suspension culture. J Ferment Technol 55:207–212.
Kato A, Kawazoe S, Soh Y (1978) Viscosity of the broth of tobacco cells in suspension culture. J Ferment Technol 56:224–228.
Kato A, Asakura A, Tsuji K, Ikeda F, Iijima M (1980) Biomass production of tobacco cells (V). Biomass production of nitrogen-reduced tobacco cells in two-stage continuous culture. J Ferment Technol 58:373–382.
Kato K, Shiozawa Y, Yamada A, Nishida K, Noguchi M (1972a) A jar fermentor culture of Nicotiana tabacum L. cell suspensions. Agric Biol Chem 36:899–902.
Kato K, Matsumoto T, Koiwai A, Mizusaki S, Nishida K, Noguchi M, Tamaki E (1972b) Liquid suspension culture of tobacco cells. Proc IVth IFS. Ferment Technol Today, pp 689-695.
Matsumoto T, Okunishi K, Nishida K, Noguchi M, Tamaki E (1971) Studies on the culture conditions of higher plant cells in suspension culture II. Effect of nutritional factors on the growth. Agric Biol Chem 35:543–551.
Matsumoto T, Okunishi K, Nishida K, Noguchi M (1972) Studies on the culture conditions of higher plant cells in suspension culture (III). Effect of physical factors and antibiotics on the growth of higher plant cells in suspension culture. Agric Biol Chem 36:2177–2183.
Murashige T, Skoog F (1962) A revised medium for rapid growth and bioassays with tobacco tissue cultures. Physiol Plant 15:473–497.
Nakashizuka M, Hashimoto T, Azechi S (1983) Sugars in the culture broth of tobacco cells. Sci Pap Odawara Salt Exp Stn. Jpn Tobacco Salt Publ Corp 19:103–120.
Noguchi M, Matsumoto T, Hirata Y, Yamamoto K, Katsuyama A, Kato A, Azechi S, Kato K (1977) Improvement of growth rates of plant cell cultures. In: Barz W, Reinhard E, Zenk MH (eds) Plant tissue culture and its bio-technological application. Springer, Berlin Heidelberg New York, pp 85–94.
Paca J, Gregr V (1977) Method for the determination of oxygen transfer coefficients (kLa) with the correction for the actual cultivation conditions. J Appl Chem Biotechnol 27:155–164.
Smart NJ, Fowler MW (1984) An airlift column bioreactor suitable for large-scale cultivation of plant cell suspensions. J Exp Bot 35:531–535.
Sugita S, To H, Yamasaki Y, Izuura M (1983a) Studies on the condition of tobacco cell culture using the flaskscale semi-bath culture, pt 2. The separated sterilization of medium and its chemical contents. Sci Pap Odawara Salt Exp Stn. Jpn Tobacco Salt Publ Corp 19:55–60.
Sugita S, To H, Yamasaki Y, Izuura M (1983b) Preparing condition of medium and the behavior of inorganic components pt 3. Jpn Tobacco Salt Publ Corp 19:61–70.
Taguchi H, Humphrey AE (1986) Dynamic measurement of the volumetric oxygen transfer coefficient in fermentation systems. J Ferment Technol 12:881–889.
Takayama S, Misawa M, Ko K, Misato T (1977) Effect of cultural conditions on the growth of Agrostemma githago cells in suspension culture and the concomitant production of an anti-plant virus substance. Physiol Plant 41:313–320.
Tanaka H (1981) Technological problems in cultivation of plant cells at high density. Biotechnol Bioeng 23:1203–1218.
Tanaka H (1982) Oxygen transfer in broths of plant cells at high density. Biotechnol Bioeng 24:425–442.
Tanaka H (1985) Technological problems in cultivation of plant cells at high density. Hakkokogaku 63:245–257.
Ulrich B, Wiesner W, Arens H (1985) Large-scale production of rosmarinic acid from plant cell cultures of Coleus blumei Benth. In: Neumann KH, Barz W, Reinhard E (eds) Primary and secondary metabolism of plant cell cultures. Springer, Berlin Heidelberg New York Tokyo, pp 293–303.
Ushiyama K (1986) Suspension culture of Panax ginseng’s root tissue. In: Yamada Y, Okada Y (eds). Plant biotechnology. Kagaku Dozin, Tokyo, pp 97–104.
Wagner F, Vogelmann H (1977) Cultivation of plant tissue culture in bioreactors and formation of secondary metabolites. In: Barz W, Reinhard E, Zenk MH (eds) Plant tissue culture and its biotechnological application. Springer, Berlin Heidelberg New York, pp 245–252.
Yuyama T, Murata A, Nagatsuka S, Nakashizuka M, Izuura M, Hashimoto T, Azechi S, Suzuki K (1985) Two stage-two flow continuous culture of tabacco plant cells. Sci Pap Odawara Exp Stn. Jpn Tobacco Salt Publ Corp 20:87–97.
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© 1988 Springer-Verlag Berlin Heidelberg
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Hashimoto, T., Azechi, S. (1988). Bioreactors for the Large-Scale Culture of Plant Cells. In: Bajaj, Y.P.S. (eds) Medicinal and Aromatic Plants I. Biotechnology in Agriculture and Forestry, vol 4. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73026-9_4
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DOI: https://doi.org/10.1007/978-3-642-73026-9_4
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