Abstract
One of the proteins synthesized by the asexual blood stage of malaria which has been studied in some detail is the precursor to the major merozoite surface antigens (PMMSA), a glycoprotein that is synthesized throughout schizogony and present on the merozoite surface in processed form (Holder & Freeman, 1982, 1984; Howard et al., 1985). Complete or partial nucleotide sequences of the gene for this protein from a number of Plasmodium falciparum strains have been reported (Holder, et al., 1985; Mackay et al., 1985; Cheung et al., 1985; Weber et al,1986). Some features of the protein and its gene will be discussed here, in particular studies we have performed with a West African (Wellcome) strain of the parasite.
Keywords
- Plasmodium Falciparum
- Variant Surface Glycoprotein
- Asexual Blood Stage
- Merozoite Surface Antigen
- Plasmodium Falciparum Strain
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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© 1987 Springer-Verlag Berlin Heidelberg
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Holder, A.A., Hillman, Y., Nicholls, S.C., Davey, L.S. (1987). Studies on the Plasmodium Falciparum 195,000 Molecular Mass Merozoite Surface Antigen Precursor. In: Chang, KP., Snary, D. (eds) Host-Parasite Cellular and Molecular Interactions in Protozoal Infections. NATO ASI Series, vol 11. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-72840-2_31
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DOI: https://doi.org/10.1007/978-3-642-72840-2_31
Publisher Name: Springer, Berlin, Heidelberg
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