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Growth of Human Renal Cell Carcinoma in Nude Mice

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Investigative Urology 2

Abstract

In metastasized renal cell carcinoma successful treatment has not been established so far (McDonald 1982). Therefore, further experimental research is necessary to attack this problem. Such studies require reliable and well defined tumor models. Xenotransplantation of human renal cell carcinoma to thymusaplastic, congenital immune-deficient nude mice seems to be a useful model system provided that the human-specific characteristics are retained. Some human kidney tumors were successfully established in nude mice and accordingly characterized (Baisch et al. 1986; Clayman et al. 1985; Höhn and Schröder 1978; Otto et al. 1981; Otto et al. 1984).

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Author information

Authors and Affiliations

  1. Urologische Klinik und Poliklinik der Universität Würzburg, Josef-Schneider-Str. 2, D-8700, Würzburg, Germany

    V. Heller, J. W. Grups & M. P. Wirth

  2. Institut für Medizinische Strahlenkunde, Universität Würzburg, Versbacher Str. 5, D-8700, Würzburg, Germany

    I. D. Bassukas

Authors
  1. V. Heller
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  2. I. D. Bassukas
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  3. J. W. Grups
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  4. M. P. Wirth
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Editor information

Editors and Affiliations

  1. Urologische Klinik und Poliklinik, im Klinikum der Johannes-Gutenberg-Universität, Langenbeckstraße 1, D-6500, Mainz, Germany

    Günther H. Jacobi

  2. Abteilung Urologie, Knappschaftskrankenhaus Bardenberg, Dr.-Hans-Böckler-Platz 1, D-5102, Würselen 1, Germany

    Herbert Rübben

  3. Urologische Klinik, Zentralklinikum, Stenglinstraße, D-8900, Augsburg, Germany

    Rolf Harzmann

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© 1987 Springer-Verlag Berlin Heidelberg

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Heller, V., Bassukas, I.D., Grups, J.W., Wirth, M.P. (1987). Growth of Human Renal Cell Carcinoma in Nude Mice. In: Jacobi, G.H., Rübben, H., Harzmann, R. (eds) Investigative Urology 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-72735-1_12

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  • DOI: https://doi.org/10.1007/978-3-642-72735-1_12

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-72737-5

  • Online ISBN: 978-3-642-72735-1

  • eBook Packages: Springer Book Archive

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