Cancer in Childhood — Solid Tumours

  • J. Plaschkes


Treatment of cancer in childhood has made enormous progress over the last 30 years. The strategies developed for leukaemia have also had a great impact on the management and treatment results of most solid tumours (Farber 1966). So far at least, somewhat paradoxically, the more effective other forms of treatment have become, the greater is the scope and role of surgery. Ultimate surgical resection still remains one of the most important prognostic factors and effective means of complete eradication of disease. The surgeon still has a central role in determining the outcome of children with solid tumours.


Germ Cell Tumour Pediatric Oncology Sacrococcygeal Teratoma Hepatocellular Carcinoma Hepatocellular Neonatal Tumour 
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  1. Allen JC, Bloom HJG, Ertel I, Evans A, Hammond D, Jones H, Levin V, et al. (1986) Brain tumours in children: current cooperative and institutional chemotherapy trials in newly diagnosed and recurrent cases. Semin Oncol 13: 110–121PubMedGoogle Scholar
  2. Anderson A, Bergdahl L (1978) Carcinoma of the colon in C children. J Pediatr Surg 1: 967–981Google Scholar
  3. Anderson JR, Wilson JF, Jenkin RDT, Meadows AT, Kersey J, Chilcote RR, Coccia P, et al. (1983) Childhood non-Hodgkin’s lymphoma. The results of a randomized therapeutic C trial comparing a 4-drug regimen (COMP) with a 10-drug regimen (LSA2-12). N Engl J Med 308: 559–565PubMedCrossRefGoogle Scholar
  4. Askin FB, Rosai J, Sibley RK, Dehner LP, McAlister WH (1979) Malignant small cell tumours of the thoracopulmo- C nary region in childhood. A distinctive clinical pathological entity of uncertain histogenesis. Cancer 43: 2438–2451PubMedCrossRefGoogle Scholar
  5. Burgers JMB, Voute PA, van Glabbeke M (1985) Adjuvant chemotherapy for osteosarcoma in limbs. Trial 20781 of the SIOP and EORTC radiotherapy/chemotherapy group. In: van Unnik W (ed) The management of bone and soft tissue sarcomas. Raven, New YorkGoogle Scholar
  6. Bader JL, Miller RW (1979) US cancer incidence in the first year of life. Am J Dis Child 133: 157–159PubMedGoogle Scholar
  7. Bader JL, Miller RW, Meadows AT, Zimmermann LE, Champion LAA, Voute PA (1980) Trilateral retinoblastoma. Lancet 2: 582–583PubMedCrossRefGoogle Scholar
  8. Baker JW, Peckham MJ, Morgan RL, Smithes DW (1972) Preservation of ovarian function in patients requiring radiotherapy for para-aortic and pelvic Hodgkin’s disease. Lancet 2: 1307–1308CrossRefGoogle Scholar
  9. Baldy O, Lemoine G, Zucker JM, Schweisguth O (1984) Pulmonary metastases in children. A study of 134 patients. J Pediatr Surg 19: 121–125CrossRefGoogle Scholar
  10. Barson AJ (1978) Congenital neoplasia (British Pediatraic Pathology Society’s experience). Arch Dis Child 53: 436Google Scholar
  11. Barson AJ, Ahmed A, Gibson AM, McDonald AM (1978) Chest wall sarcoma of childhood with a good prognosis. Arch Dis Child 53: 882–889PubMedCrossRefGoogle Scholar
  12. Beckwith JB (1983) Wilms’ tumour and other renal tumours in childhood. A selective review from the National Wilms’s Tumour Study Pathology Centre. Hum Pathol 14: 481–492PubMedCrossRefGoogle Scholar
  13. Beddis JR, Noblett H, Mott MG (1984) Effective chemotherapy for metastatic sacrococcygeal teratoma. Med Pediatr Oncol 12: 231–234PubMedCrossRefGoogle Scholar
  14. Bienaymé J, Gross P (1976) Tumeurs malignes du pancreas chez l’enfant. Ann Chir Infant 17: 131–155Google Scholar
  15. Barnes L, Verbin R, Goodman M et al. (1985) Diseases of bones and joints. In: Barnes L. (ed) Surgical pathology of head and neck. Dekker, New YorkGoogle Scholar
  16. Birch JH, Hartley AL, Marsden HB, Harns M, Swindell R (1984) Excess risk of breast cancer in mothers of children with soft tissue sarcoma. Br J Cancer 49: 325–331PubMedCrossRefGoogle Scholar
  17. Birch JM, Marsden HB, Blair V, Hartley AL (1987) An epidemiological study of germ cell tumours in children (Abstr). Meeting of the International Society of Pediatric Oncology, JerusalemGoogle Scholar
  18. Bleyer W, Millstein J, Balias F, Pendergrass T, Chard R, Hart-mann J (1983) 8 drugs in one day. Chemotherapy for brain tumours - a new approach and rationale for preirradiation chemotherapy (Abstr). Med Pediatr Oncol 11: 213Google Scholar
  19. Bolande RP (1971) Benignity of neonatal tumours and concept of cancer regression in early life. Am J Dis Child 122: 12–14PubMedGoogle Scholar
  20. Bousvaros A, Kirks DH, Grossmann H (1986) Imaging in neuroblastoma. An overview. Pediatr Radiol 16: 89–106PubMedCrossRefGoogle Scholar
  21. Brodeur GM, Seeger Schwab, et al. (1984) Amplification of N Myc in untreated human neuroblastoma correlates with advanced stage disease. Science 224: 1121–1124PubMedCrossRefGoogle Scholar
  22. Bucalessi P, Veronesi U, Emanuelli H, Fossati-Bellani F (1976) Tumori infantili. Ambrosiono, MilanoGoogle Scholar
  23. Campanacci M, Bacci G, Bentoni F, et al. (1981) The treatment of osteosarcoma of the extremities. Twenty years experience at the Instituto Ortopedico Rizzoli. Cancer 48: 1569–1581PubMedCrossRefGoogle Scholar
  24. Camprodon R, Quintanilla E (1984) Successful long term results with resection of pancreatic carcinoma in children. Favourable progress for an uncommon neoplasm. Surgery 95: 420–426PubMedGoogle Scholar
  25. Castelberry RP, Kelly DR, Wilson ER, Cain WS, Solter MR (1984) Childhood liposarcoma. Cancer 54: 579–584CrossRefGoogle Scholar
  26. Chang CH, Houspian EM, Herbert CJ (1969) An operative staging system and megavoltage radiotherapy technique for cerebellar medulloblastoma. Radiology 93: 1351PubMedGoogle Scholar
  27. Choux M, Lena G (1982) Le medulloblastome. Neurochirurgie [Suppl 1] 28Google Scholar
  28. Cohen ME, Duffner PK (1984) Brain tumours in children Principles of diagnosis and treatment. Raven, New YorkGoogle Scholar
  29. D’Angio GJ, Evans AE, Breslow E, et al. (1981) The treatmem of Wilms’ tumour. Results of the second National Wilms’ Tumour Study. Cancer 47: 2302–2311PubMedCrossRefGoogle Scholar
  30. De Kraker J, Voûte PA (1986) The role of ifosfamide in pediatric soft tissue sarcoma (Abstr). 17th SIOP Annual Meeting VeniceGoogle Scholar
  31. De Kraker J, Voûte PA, Burgers JM (1983) The sandwich scheme - a new approach in the treatment of medulloblastoma patients (Abstr). 13th International Congress of Chemotherapy, ViennaGoogle Scholar
  32. Deutsch M (1984) The impact of myelography on the treatment results for medulloblastoma. Int J Pediatr Oncol Biol Phys 10: 999–1003CrossRefGoogle Scholar
  33. Donaldson SS, Kaplan HS (1982) Complications of treatmenl of Hodgkin’s disease in children. Cancer Treat Rep 66: 977–989PubMedGoogle Scholar
  34. Donath A, Kaeser H, Roos B, Ziegler W, Oetliker O, Colombo JP, Bettex M (1965) Le pheochromocytome familiale; discussion de la malignite et du hereditaire a propos d’un cas chez l’enfant a secretion particuliere. Helv Paediatr Acta 20: 1–18PubMedGoogle Scholar
  35. Douglas EC, Green AO, Wrenn E, Champion J, Sipp M, Pratt CB (1985) Effective cisplatin DDP based chemotherapy in the treatment of hepatoblastoma. Med Pediatr Oncol 13: 187–190CrossRefGoogle Scholar
  36. Draper GJ, Birch JM, Ittel JF, Wilson LM, Lack I, Marsden HB, Jones PHM, et al. (1982) Childhood cancer incidence. Survival and mortality. HMSO, London, no 37Google Scholar
  37. Ehrenbard LT, Chaganti RSK (1981) Cancer in the fetal hy-dantoin syndrome. Lancet 2: 97PubMedCrossRefGoogle Scholar
  38. Elsworth RM (1969) The practical management of retinoblastoma. Trans Am Opthalmol Soc 67: 462–534Google Scholar
  39. Enneking WF (1985) International symposium on limb salvage in musculoskeletal oncology, OrlandoGoogle Scholar
  40. Erikson RP, Gondas B (1972) Alternative explanation of the different behaviour of ovarian and testicular teratomas. Lancet 1: 1307–1308Google Scholar
  41. Etcubanas E, Histu HO, Sklar M, Pratt C (1985) Influence of different treatment modalities on the curability of childhood rhabdomyosarcoma of the head and neck. Eur J Pediatr Haematol OncolGoogle Scholar
  42. Evans AE, D’Angio GJ, Randolph J (1971) A proposed staging system for children with neuroblastoma. Children’s Cancer Study Group. Cancer 27: 374–378PubMedCrossRefGoogle Scholar
  43. Evans AE, Land VJ, Newton WA, Randolph JG, Sather HN, Tefft M (1982) Combination chemotherapy (vincristine, adriamycin, cyclophosphamide and 5 FU) in the treatment of children with malignant hepatoblastoma. Cancer 50: 821–826PubMedCrossRefGoogle Scholar
  44. Exelby PR (1980) Malignant lymphoma in children. World J Surg 4: 49–62PubMedCrossRefGoogle Scholar
  45. Exelby PR, Filler RM, Grossfeld JL (1975) Liver tumours in children in the particular reference to hepatoblastoma and hepatocellular carcinoma. J Pediatr Surg 10: 329–337PubMedCrossRefGoogle Scholar
  46. Farber S (1966) Chemotherapy in the treatment of leukemia and Wilms’ tumour. JAMA 198: 826–836PubMedCrossRefGoogle Scholar
  47. Filler RM, Traggis NJ, Jaffe N, et al. (1972) Favourable outlook for children with mediastinal neuroblastoma. J Pediatr Surg 7: 136–138PubMedCrossRefGoogle Scholar
  48. Flamant F, Hill C (1984) The improvement in survival associated with combined chemotherapy in childhood rhabdomyosarcoma. A historical comparison of 345 patients treated at the same centre. Cancer 53: 2417–2421PubMedCrossRefGoogle Scholar
  49. Flamant F, Schwarz L, Delons E, Caillaud J, Hartmann M, Le-merle J (1984) Seminomatous non malignant cell tumours in children. Cancer 54: 1687–1691PubMedCrossRefGoogle Scholar
  50. Flamant F, Rodary CH, Voute PA, Otten J (1985) Primary chemotheray in the treatment of rhabdomyosarcoma in children. Trial of the International Society of Pediatric Oncology SIOP (Preliminary results). Radiother Oncol 3: 187–297CrossRefGoogle Scholar
  51. Fossati-Bellani F, Kenda F, Lombardi F, Gianni C, Gasparini M, Pizetti P, Musumeci R, Bonnadonna G (1984) Childhood Hodgkin’s disease. Treatment with ABVD chemotherapy and limited field irradiation (Abstr). 2nd International Conference on Malignant Lymphoma, LuganoGoogle Scholar
  52. Gale GB, D’Angio GJ, et al. (1982) Cancer in neonates. The experience at the Children’s Hospital of Philadelphia. Pediatrics 70: 409–413PubMedGoogle Scholar
  53. Gasparini M, Barni S, La Hauda A, et al. (1977) Ten years experience with Ewing’s sarcoma. Tumori 63: 77–89PubMedGoogle Scholar
  54. Gasparini M, Lombardini F, Gianni C, Lavati C, Fossati-Bellani F (1983) Childhood rhabdomyosarcoma with meningeal extension. Results of chemotherapy including central nervous system prophylaxis. Am J Clin Oncol 6: 393PubMedCrossRefGoogle Scholar
  55. Gehan EA, Glover FN, Maurer HM, et al. (1981) Prognostic factors in children with rhabdomyosarcoma. NCI Monogr 56: 83Google Scholar
  56. Gilles FH, Leviton A, Hedley-White T, et al. (1983) Childhood brain tumour update. Hum Pathol 14: 835–845CrossRefGoogle Scholar
  57. Glass AG, Fraumeni JR (1970) Epidemiology of bone cancer in children. JNCI 44: 187–199PubMedGoogle Scholar
  58. Gnudi S, Picci P, Gherlinzoni F, Bacci G, Putti C (1983) Adjuvant chemotherapy for localised Ewing’s sarcoma. Ten years experience in 121 cases at the Instituto Ortopedico Rizzoli. In: Spitzy KH, Karrer K. (eds) Proceedings of the 13th International Congress of Chemotherapy, Vienna. 251:19–22Google Scholar
  59. Godano F, Fabrici B, Ricci RF (1987) Stereotactic surgery in the management of deep intracranial lesions in infancy and adolescents. Child Nerv Syst 3: 85–88CrossRefGoogle Scholar
  60. Goorin AM, Apelson HT, Frei E (1985) Osteosarcoma - fifteen years later. N Engl J Med 313: 1637–1642PubMedCrossRefGoogle Scholar
  61. Green DM (1983) The diagnosis and treatment of germ cell tumours in infants and children. Cancer Treat Rev 10: 265–288PubMedCrossRefGoogle Scholar
  62. Grosfeld JL, Ballantine RL, Bachner J (1978) Experience with second look operations in pediatric solid tumours. J Pediatr Surg 13: 275–286PubMedCrossRefGoogle Scholar
  63. Gutjahr P (1986) Krebs bei Kindern und Jugendlichen. Klinik und Praxis. Deutscher Arzte Verlag, CologneGoogle Scholar
  64. Halpern S (1981) Thyroid carcinoma in childhood. Med Pediatr Oncol 9: 143–157PubMedCrossRefGoogle Scholar
  65. Harmer HM, et al. (1982) The TNM classification of pediatric tumours. UICC, GenevaGoogle Scholar
  66. Harms D, Gottschalk J, Yanig U (1983) Pathologische Anatomie der Keimzelltumoren (besonders Hodentumoren bei Kindern). Klin Padiatr 195: 196–200PubMedCrossRefGoogle Scholar
  67. Hawkins E (1987) Pathology of germ cell tumours (Abstr). Meeting of the International Society of Pediatric Oncology, JerusalemGoogle Scholar
  68. Hawkins MM, et al. (1987) Incidence of second primary tumours among childhood cancer survivors. Br J Cancer 56: 339–347PubMedCrossRefGoogle Scholar
  69. Hays FA, Green AA, Histu HO, et al. (1983) Surgicopathological staging of neuroblastoma. Prognostic significance of regional lymphoid metastases. J Pediatr 102: 59CrossRefGoogle Scholar
  70. Hays DM (ed) (1986 a) Pediatric surgical oncology. Grune and Stratton, OrlandoGoogle Scholar
  71. Hays DM (1986 b) Rhabdomyosarcoma and other soft tissue tumours. In: Hays DM. (ed) Pediatric surgical oncology. Grune and Stratton, OrlandoGoogle Scholar
  72. Hays DM, Ternberg JL, Clen TT, et al. (1984) Complication related to 234 staging laparotomies performed in the Inter-group Hodgkin’s Disease in Childhood study. Surgery 96: 471–478PubMedGoogle Scholar
  73. Hazebroock FW, Vos J, Voute PA (1979) Experience of surgical resection of pulmonary metastases of osteosarcomas in children. Ned Tijdschr Geneeskd 123: 192–195Google Scholar
  74. Herbst AL, Ulfelder H, Posckanzer DC (1971) Adenocarcinoma of the vagina. N Engl J Med 284: 878–881PubMedCrossRefGoogle Scholar
  75. Hirt A, Baumgartner C, Imbach P. Liithy A, Wagner HP (1984) Differentiation and cytokinetic analyses of normal and neoplastic lymphoid cells in B and T cell malignancies of childhood. Br J Haematol 58: 241–248PubMedCrossRefGoogle Scholar
  76. Holton CP, Burrington JD, Hatch EI (1975) A multiple chemo-therapeutic approach to the management of hepatoblastoma. A preliminary report. Cancer 35: 1083–1087PubMedCrossRefGoogle Scholar
  77. International Society of Pediatric Oncology (1987) Germ cell tumours. Meeting of the International Society of Pediatric Oncology, Jerusalem Jones PG, Campbell PM (eds) (1976) Tumours of infancy and childhood. Blackwell, OxfordGoogle Scholar
  78. Jurgens H, Gobel V, Michaelis J, Ramach W, Ritter J, Sauer R, Treuner J, et al. (1985) Die co-operative Ewing Sarkoma Studie, CESS 81 der GPO. Analyse nach 4 Jahren. Klin Pae-diatr 197: 225–232Google Scholar
  79. Kasai M, Watanabe I (1970) Histological classification of liver cell carcinoma in infancy and childhood and its clinical evaluation. A study of 70 cases collected in Japan. Cancer 25: 557–563CrossRefGoogle Scholar
  80. Kilman JW, Clatworthy HW, Newton WA, et al. (1973) Reasonable surgery for rhabdomyosarcoma. Ann Surg 178: 346–357PubMedCrossRefGoogle Scholar
  81. Kinnier-Wilson LM, Draper GJ (1974) Neuroblastoma, its natural history and prognosis. A study of 487 cases. Br Med J 3: 301–307CrossRefGoogle Scholar
  82. Kissane JM, Askin FB, Foulkes M, Stratton LB, Shirely SF (1983) Ewing’s sarcoma of bone: clinicopathologic aspects of 303 cases from the Intergroup Ewing’s Sarcoma Study. Hum Pathol 14: 773–779PubMedCrossRefGoogle Scholar
  83. Knudson AG (1978) Retinoblastoma - a prototypic hereditary neoplasma. Semin Oncol 5: 57–60PubMedGoogle Scholar
  84. Koop E (1972) The neuroblastoma. Progr Pediatr. Surg 14: 14Google Scholar
  85. Kotz E (1983) Proceedings of the 2nd International Workshop in the Design and Application of Tumour Prosthesis for Bone and Joint Reconstruction. Vienna 5–8 SeptGoogle Scholar
  86. Krush AT et al. (1988) Hepatoblastoma, pigmented ocular fundus and jaw lesions in Gardner syndrome. Am J Med Genet 29: 323–333PubMedCrossRefGoogle Scholar
  87. Le Floch O, Donaldson S, Kaplan H (1976) Pregnancy following oophoropexy and total modal irradiation in women with Hodgkin’s disease. Cancer 38: 2263–2268CrossRefGoogle Scholar
  88. Lemerle J, Bloch-Michel E, Campinchi R, Chassagne D, Saraz-zin D (1978) Chemotherapy as primary treatment in children with bilateral retinoblastoma. Proc Am Soc Clin Oncol 19: 416Google Scholar
  89. Lemerle J, Voute PA, Tournade MF, Rodary C, Delemarre JF (1983) Effectiveness of preoperative chemotherapy in Wilms’ tumour. Results of an International Society of Paediatric Oncology (SIOP) clinical trial. J Clin Oncol 1 (10): 604–609PubMedGoogle Scholar
  90. Lewis MM (1986) The use of an expandable and adjustable prosthesis in the treatment of childhood malignant bone tumours of the extremity. Cancer 57: 499–502PubMedCrossRefGoogle Scholar
  91. Link MP, Goorin AM, Miser AW, Green AA, Pratt CB (1986) The effect of adjuvant chemotherapy on relapse free survival in patients with osteosarcoma of the extremity. N Engl J Med 3/4: 1600–1606CrossRefGoogle Scholar
  92. Littman P, D’Angio GJ (1981) Radiation therapy in the neonate. Am J Pediatr Hematol Oncol 3: 279–285PubMedGoogle Scholar
  93. Machin GA (1980) Persistent renal blastoma (nephroblastomatosis) as a frequent precursor of Wilms’ tumour. A clinical and pathological review. Am J Pediatr Hematol Oncol 2: 253–261PubMedGoogle Scholar
  94. Malpas JS, Freeman JE, Baxton A (1976) Radiotherapy and adjuvant chemotherapy for childhood rhabdomyosarcoma. Br Med J 1: 247–249PubMedCrossRefGoogle Scholar
  95. Mann HW, Evans AE, Siegel SE, et al. (1985) Prognostic importance of serum ferritin in patients in stage III and IV neuroblastoma. The CCSG experience. Cancer Res 45: 2843–2845Google Scholar
  96. Marcove RC, Abu Zair K (1984) En bloc surgery for osteosarcoma, analysis and review of 90 cases. Bull NY Acad Med 60:748–758Google Scholar
  97. Marcove RC, Rosen G (1980) Radical en bloc excision for Ewing’s sarcoma. Clin Orthop 153: 61–68Google Scholar
  98. Marsden HB, Lennox EL, Lawler W, Kinnier-Wilson LM (1980) Bone metastases in childhood renal tumors. Br J Cancer 41: 875–879PubMedCrossRefGoogle Scholar
  99. Mauch PM, Weinstein H, Botnick L, Belli J, Cassady JD (1983) An evaluation of long term survival and treatment. Complications in children with Hodgkin’s disease. Cancer 51: 925–932PubMedCrossRefGoogle Scholar
  100. McDivitt RW, Stewart FW (1981) Breast carcinoma in children. JAMA 195: 144–147Google Scholar
  101. Meadows AT, Baum E, Fossati-Bellani F, Green D, Jenkin RDT, Marsden B, Nesbit M, et al. (1985) Second malignant neoplasms. An update from the Late Effects study group. J Clin Oncol 3: 532–538PubMedGoogle Scholar
  102. Mendenhall CM, Marcus RB, Enneking WF, Springfield DS, Thar TL, Million RR (1983) The prognostic significance of soft tissue extension in Ewing’s sarcoma. Cancer 51: 913–917PubMedCrossRefGoogle Scholar
  103. Milév, Meadows AT, D’Angio GH (1982) Incidence of second malignant neoplasms in childhood: results of an international study. Lancet 2: 1326–1331Google Scholar
  104. Mulvihill JJ (1985) Clinical ecogenetics. Cancer in families. N Engl J Med 312: 1569–1570PubMedCrossRefGoogle Scholar
  105. Murphy SB (1980) Classification, staging and end results of treatment of childhood non-Hodgkin’s lymphomas: dissimilarities from lymphomas in adults. Semin Oncol 7: 332–339PubMedGoogle Scholar
  106. Natman MG (1987) Screening for neuroblastoma. Lancet 2: 656–666Google Scholar
  107. Nesbit M, Perez CA, Tefft M, Burgert EO, Vietti TJ, Kissane J, Pritchard DJ, Geman EA (1981) Multimodal therapy for the management of primary non metastatic Ewing’s sarcoma of bone. An intergroup study. Natl Cancer Inst Monogr 56: 255–262PubMedGoogle Scholar
  108. NIH (1984) Limb sparing treatment. Adult soft tissue and osteogenic sarcoma (Abstr). NIH Cancer development conferenceGoogle Scholar
  109. Ninane J, Pritchard J, Morris-Jones PM, et al. (1982) Stage II neuroblastoma - adverse prognostic significance of lymph node involvement. Arch Dis Child 57: 438–441PubMedCrossRefGoogle Scholar
  110. Ohtomo K, Araki T, Yashiro N, Iio M (1983) Pulmonary blastoma in children. Radiology 147: 101–183PubMedGoogle Scholar
  111. Packer RJ, Sutton LN, Rorke LB (1984) Prognostic importance of cellular differentiation in medulloblastoma in childhood. J Neurosurg 61 (2): 296–301PubMedCrossRefGoogle Scholar
  112. Palmer N, Sachs N, Foulkes M (1982) Histopathology and prognosis in rhabdomyosarcoma (IRSI). Proc Am Soc Clin Oncol 1: 170Google Scholar
  113. Pellerin D, Nihoul-Fekete C, Revillon Y, Fernandes P (1982) Place of Surgery in Neuroblastoma. Arch Franc Pediat 39: 13–16PubMedGoogle Scholar
  114. Pendergrass TW (1976) Congenital anomalies in children with Wilms’ tumour. Cancer 37: 403–408PubMedCrossRefGoogle Scholar
  115. Perilongo G et al. (1987) Undifferentiated (embryonal) sarcoma of the liver in childhood. Results of a retrospective Italian study. Tumor 73: 213–217Google Scholar
  116. Pichler E, Kogelnik HD, Reinatz G, et al. (1987) Ergebnisse der Therapie des Medulloblastoms in den letzten 15 Jahren. Strahlentherapie 157: 508–515Google Scholar
  117. Pinkerton R, McElwain T, Horwich A, Prilelardy J (1987) Car-toplatin VP 16 bleomycin in children with malignant germ cell tumours (Abstr). Meeting of the International Society of Pediatric Oncology, JerusalemGoogle Scholar
  118. Plaschkes J (1974) Congenital fibromatosis, localized and generalized forms. J Pediatr Surg 9: 95–101PubMedCrossRefGoogle Scholar
  119. Plaschkes J (1981) Congenital dumb-bell neuroblastoma with paraplegia - how to treat. Excerpta Med Int Congr Ser 57: 188–192Google Scholar
  120. Raney RB, Palmer N, Sutow W, Baum E, Ayala A (1983) Renal cell Carcinoma in children. Med Pediatr Oncol 1: 91–98CrossRefGoogle Scholar
  121. Rao BN, Champion JE, Pratt CB, et al. (1983) Limb salvage procedures for children with osteosarcoma. An alternative to amputation. J Pediatr Surg 18: 901–908PubMedCrossRefGoogle Scholar
  122. Rao BN, Pratt CB, Fleming ID, Dilawari RA, Green AA, Austin B (1985) Colon Cancer in Children and Adolescents. Cancer 55: 1322–1326PubMedCrossRefGoogle Scholar
  123. Rorke LB (1983) The cerebellar medulloblastoma and its relationship to primitive neuroectodermal tumours. J Exp Neu-ropathol Exp Neurol 42: 1–15CrossRefGoogle Scholar
  124. Rosen G, Caparos B, Nirnberg A, Marcove RC, Huvos AG, Kosloff C, Lane J, Murphy L (1981) Ewing’s sarcoma - a ten years’ experience with adjuvant chemotherapy. Cancer 41: 2204–2213CrossRefGoogle Scholar
  125. Rosen G, Caparros B, Huvos AC, et al. (1982) Preoperative chemotherapy of osteogenic sarcoma. Selection of postoperative adjuvant chemotherapy based on the response of primary tumour to preoperative chemotherapy. Cancer 49: 1221–1230PubMedCrossRefGoogle Scholar
  126. Ryden SE, Drake RM, Franciosi RA (1975) Carcinoid tumours of the appendix in children. Cancer 36: 1538–1542PubMedCrossRefGoogle Scholar
  127. Scales JJ (1983) Bone and joint replacement for the preservation of limbs. Br J Hosp Med 29: 220–232Google Scholar
  128. Schellong J et al. (1986) Prediction of splenic involvement in children with Hodgkin’s disease. A retrospective statistical analysis of 134 patients in the German therapy study DAL HD 78. Cancer 57: 2049–2056PubMedCrossRefGoogle Scholar
  129. Schnaufer L, Koop CE (1975) Silastic abdominal patch for temporary hepatomegaly in stage VS neuroblastoma. J Pediatr Surg 10: 73–75PubMedCrossRefGoogle Scholar
  130. Schulte FJ (1987) Pineal region tumours of childhood. Eur J Pediatr 146: 233–245PubMedCrossRefGoogle Scholar
  131. Schweisguth O (1979) Tumeurs solides de l’enfant. Flammarion, ParisGoogle Scholar
  132. Shimada H, Chatten J, Newton WA, et al. (1984) Histopathologic factors in neuroblastic tumours. JNCI 73: 405–466PubMedGoogle Scholar
  133. Siegel SE, Lang WE, Harlow PJ, et al. (1980) Patterns of urinary catecholamine metabolite excretion in neuroblastoma. In: Evans AE (ed) Advances in neuroblastoma research. Raven, New YorkGoogle Scholar
  134. Siegel SE, Meran RG (1981) Problems in the chemotherapy of cancer in the neonate. Am J Pediatr Hematol Oncol 3: 287–299PubMedGoogle Scholar
  135. SIOP (1987) The role of MIBG in therapy, diagnosis and monitoring of neuroblastoma. Proceedings of the 4th International Workshop on Pediatric Oncology. Med Pediatr Oncol 15: 155–227Google Scholar
  136. Stevens PS, Eckstein HB (1976) Ureteral metastases from Wilms’. J Urol 115: 467–468PubMedGoogle Scholar
  137. Todani T, Shimada K, Watanabe Y, Toki A, Fuji T, Uhushiwara N (1988) Frantz’s tumour - a papillary and cystic tumour of the pancreas in girls. J Pediatr Surg 23: 116–121PubMedCrossRefGoogle Scholar
  138. Treuner J, Altmannsberger D, Niethammer D (1986) Soft tissue sarcomas. In: Riehm H (ed) Malignant neoplasma in childhood and adolescence. Karger, BaselGoogle Scholar
  139. Tschuctida Y, Endo Y, Saido K et al. (1978) Feto-protein levels according to age. J Pediatr Surg 13: 155–156CrossRefGoogle Scholar
  140. Van Buningon EN, Delemarre JFM, de Kraker J (1987) Germ cell tumours of the ovary. Results of the Amsterdam Group (Abstr). Meeting of the International Society of Pediatric Oncology, JerusalemGoogle Scholar
  141. Van Eys J, Cangir A, Coody D, Smith B (1985) Preoperative chemotherapy. MOPP regimen as primary chemotherapy for brain tumours. J Neurooncol 3: 237–243PubMedCrossRefGoogle Scholar
  142. Vos A, Voûte PA, Kraker I (1982) Influence of chemotherapy on radical excision of childhood hepatoblastoma (Abstr). 1st Congess of the European Society of Surgical Oncology, Amsterdam Voute PA, Barrett A, Bloom JB, Lemerle J, Niedhardt MK. (eds) (1986) Cancer in children - clinical management. Springer, Berlin Heidelberg New YorkGoogle Scholar
  143. Wagner HP, Kaser H (1983) The role of surgery, radiotherapy and chemotherapy in the treatment of neuroblastoma. In: Rickham PP, Hecker WC, Prevot J (eds) Progress in Pediatric Surgery, Urban and Schwarzenberg, MunichGoogle Scholar
  144. Weinberg ME, Finegold MJ (1983) Primary hepatic tumours of childhood. Hum Pathol 14: 512–537PubMedCrossRefGoogle Scholar
  145. Weller CV (1941) The inheritance of retinoblastoma and its relationship to practical eugenics. Cancer Res 1: 517Google Scholar
  146. Wharam MD, Klein JL, Leichner PK, Order SE (1987) Preliminary experience with radioisotope labelled immunoglobulin for therapy of pediatric hepatoma (Abstr). 19th Meeting of the International Society of Pediatric Oncology, JerusalemGoogle Scholar
  147. Winship T, Rosvoll R (1961) Thyroid carcinoma in childhood. Final report on a 26 year study. Cancer 14: 734–743PubMedCrossRefGoogle Scholar
  148. Yamamuro K (1987) International symposium on limb salvage in musculoskeletal oncology, KyotoGoogle Scholar
  149. Young JL, Miller RW (1975) Incidence of malignant tumours in US children. J Pediatr 86: 254–258PubMedCrossRefGoogle Scholar
  150. Zucker JM, Margulis E (1979) Radiotherapy of postoperative minimal residual disease in neuroblastoma. Cancer Res 68: 423Google Scholar
  151. Zucker JM, Henry-Amar M, Sarrazin D, Black R, Patte C, Schweisguth O (1983) Intensive systematic chemotherapy in localised Ewing’s sarcoma in childhood. A historical trial. Cancer 52: 415–423PubMedCrossRefGoogle Scholar

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