Progress in Treatment of Advanced Non-Hodgkin’s Lymphoma in Children — Report on Behalf of the Polish Children’s Leukemia/Lymphoma Study Group
It is well known that children with nonHodgkin’s lymphoma (NHL) are highly curable by modern treatment schedules . As has been reported, with the LSA2L2 protocol the Polish Children’s Leukemia/Lymphoma Study Group was able to cure about 90% of NHL children in stages I and II . However, the outcome of disseminated NHL, particularly with initial central nervous system (CNS) or bone marrow (BM) involvement and B-cell histology remained unsatisfactory . Therefore, between 1983 and 1986 two other therapy modalities, COAMP  and the Murphy  protocols were applied for children with nonlocalized NHL.
KeywordsLymphoma Cobalt Leukemia Hydrocortisone Methotrexate
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