Progress in Treatment of Advanced Non-Hodgkin’s Lymphoma in Children — Report on Behalf of the Polish Children’s Leukemia/Lymphoma Study Group
It is well known that children with nonHodgkin’s lymphoma (NHL) are highly curable by modern treatment schedules . As has been reported, with the LSA2L2 protocol the Polish Children’s Leukemia/Lymphoma Study Group was able to cure about 90% of NHL children in stages I and II . However, the outcome of disseminated NHL, particularly with initial central nervous system (CNS) or bone marrow (BM) involvement and B-cell histology remained unsatisfactory . Therefore, between 1983 and 1986 two other therapy modalities, COAMP  and the Murphy  protocols were applied for children with nonlocalized NHL.
KeywordsTherapy Modality Lymphoma Study Group Polish Child Modem Trend Initial Central Nervous System
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