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Verbesserte In-vitro-Diagnostik der Allergie gegen die Schimmelpilze Alternaria tenuis und Cladosporium herbarum bei Kindern

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Chronische Erkrankungen der Atemwege im Kindesalter

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Zusammenfassung

Sensibilisierungen der Atemwege gegen Schimmelpilzallergen sind im Kindesalter selten. Verglichen mit anderen Allergenen wie Pollen oder Hausstaubmilben ist die Diagnose häufig schwer zu stellen. Dies beruht hauptsächlich auf dem Fehlen von Allergenextrakten mit guter Sensitivität und Spezifität zur Anwendung in der In-vitro- und In-vivo-Diagnostik (Aas et al. 1980; Salvaggio u. Aukrust 1981; Schumacher u. May 1972; Yunginger et al. 1976). Deshalb wurde versucht, gereinigte und standardisierte Testextrakte herzustellen. Die Überlegenheit dieser Extrakte konnte im Prick-test und im Radioallergosorbent-Test demonstriert werden (Aas et al. 1980; Hoffman 1981; Mailing 1985; Mailing et al. 1985). Ziel dieser Studie war es, die diagnostischen Möglichkeiten von teilweise gereinigten und standardisierten lyophilisierten Extrakten von Alternaria und Cladosporium in der In-vitro-Allergiediagnostik zu untersuchen.

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Authors and Affiliations

  1. Kinderklinik und Poliklinik, Universität Erlangen-Nürnberg, Loschgestraße 15, 8520, Erlangen, Deutschland

    T. Zimmermann

  2. Institut für Klinische Immunologie, Universität Erlangen, Deutschland

    H. G. Nüsslein, M. Baum, C. Fuchs & K. Kölble

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  1. T. Zimmermann
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  2. H. G. Nüsslein
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  3. M. Baum
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  4. C. Fuchs
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  5. K. Kölble
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Editors and Affiliations

  1. Kinderkrankenhaus Seehospiz „Kaiserin Friedrich“, 2982, Staatsbad Norderney, Germany

    Burkhard Schmidt-Redemann (Ärztlicher Direktor) & Sandor Gonda (Leitender Oberarzt) (Ärztlicher Direktor) &  (Leitender Oberarzt)

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© 1987 Springer-Verlag Berlin Heidelberg

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Zimmermann, T., Nüsslein, H.G., Baum, M., Fuchs, C., Kölble, K. (1987). Verbesserte In-vitro-Diagnostik der Allergie gegen die Schimmelpilze Alternaria tenuis und Cladosporium herbarum bei Kindern. In: Schmidt-Redemann, B., Gonda, S. (eds) Chronische Erkrankungen der Atemwege im Kindesalter. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-72573-9_19

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  • DOI: https://doi.org/10.1007/978-3-642-72573-9_19

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-17658-9

  • Online ISBN: 978-3-642-72573-9

  • eBook Packages: Springer Book Archive

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