Abstract
Information about the topology of Na+/K+-ATPase subunits in the cell membrane has been obtained from their primary sequences and hydropathy plots combined with site-specific labelling, immunological and proteolytic digestion studies. The N- and C-termini have been located on the cytoplasmic side by Antolovic et al. (1) on right side-out vesicles using immunological techniques. The number and location of membrane spanning regions is still a matter of dispute as the hydropathy plots in the C-terminal area do not give any clear answer (4).
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References
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© 1994 Dietrich Steinkopff Verlag GmbH & Co. KG, Darmstadt
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Skriver, E., Antolovic, R., Møller, J.V. (1994). Cytoplasmic and Extracellular Domains in Two-dimensional Crystals of Na+/K+-ATPase. In: Bamberg, E., Schoner, W. (eds) The Sodium Pump. Steinkopff. https://doi.org/10.1007/978-3-642-72511-1_57
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DOI: https://doi.org/10.1007/978-3-642-72511-1_57
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