Skip to main content

Sp1 and an E-Box Binding Protein Regulate Na+/K+-ATPase α2-Subunit Gene

  • Chapter
  • 21 Accesses

Abstract

Na+/K+-ATPase α2 subunit gene exhibits tissue-specific and developmental patterns of expression in the rat. For example, it is expressed specifically in muscle and neural tissues. The mRNA level of the α2 subunit gene in muscle tissue increases dramatically during rat myogenesis (3). In this study, we report promoter analysis of rat Na,K-ATPase α2 subunit gene (Atp1a2). To identify cis elements and trans-acting factors, we used L6 rat myoblast cells as a model for skeletal muscle.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Davis RL, Cheng P-F, Lassar AB, Weintraub H (1990) The MyoD DNA binding domain contains a recognition code for muscle-specific gene activation. Cell 60: 733–746

    Article  PubMed  CAS  Google Scholar 

  2. Herschlag D, Johnson FB (1993) Synergism in transcriptional activation: a kinetic view. Genes Dev 7: 173–179

    Article  PubMed  CAS  Google Scholar 

  3. Orlowski J, Lingrel JB (1988) Tissue-specific and developmental regulation of rat Na,K-ATPase catalytic a isoform and β subunit mRNAs. J. Bio Chem 263: 10436–10442

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1994 Dietrich Steinkopff Verlag GmbH & Co. KG, Darmstadt

About this chapter

Cite this chapter

Ikeda, K., Nagano, K., Kawakami, K. (1994). Sp1 and an E-Box Binding Protein Regulate Na+/K+-ATPase α2-Subunit Gene. In: Bamberg, E., Schoner, W. (eds) The Sodium Pump. Steinkopff. https://doi.org/10.1007/978-3-642-72511-1_4

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-72511-1_4

  • Publisher Name: Steinkopff

  • Print ISBN: 978-3-642-72513-5

  • Online ISBN: 978-3-642-72511-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics