Efficacy and duration of action of three doses of Zatebradine (ULFS 49 CL) in patients with chronic angina pectoris compared to placebo

  • W. Baiker
  • E. v. Czako
  • M. Keck
  • G. Nehmiz
Conference paper


Zatebradine (ULFS 49 CL) is a member of a new class of drugs, the so-called sinus node inhibitors that specifically reduce the spontaneous rate of depolarization of the pacemaker cells in the sino-atrial node [5, 6], leading to a decrease in heart rate.


Myocardial Blood Flow Chronic Stable Angina Anginal Attack Total Exercise Duration Sublingual Nitrate 
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Copyright information

© Dr. Dietrich Steinkopff Verlag GmbH & Co. KG, Darmstadt 1991

Authors and Affiliations

  • W. Baiker
    • 1
    • 2
  • E. v. Czako
    • 3
  • M. Keck
    • 4
  • G. Nehmiz
    • 5
  1. 1.Department of Medicine, CardiologyDr. Karl Thomae GmbHBiberachGermany
  2. 2.Clinical ResearchBoehringer Ingelheim Pharmaceuticals Inc.RidgefieldUSA
  3. 3.Salzetalklinik der LVA WestfalenBad SulzuflenGermany
  4. 4.Fachklinik für Herz- und Kreislaufkrankheiten der LVABad Münster am SteinGermany
  5. 5.Department of Medicine, BiometryDr. Karl Thomae GmbHBiberachGermany

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