Cardiac Pacing pp 901-908 | Cite as

Creation of Experimental Atrioventricular Block using DC Shock via a Percutaneous Transaortic Electrode Catheter

  • O.-J. Ohm
  • Leonard S. Dreifus
  • H. Mitamura
  • Ch. Sauermelch
  • H. Haupt
  • S. Vail
  • M. Schaffenburg
  • E. L. Michelson


The need to develop an experimental model in the closed chest animal for the study of hemodynamic and electrophysiologic effects of various physiologic and pharmacologic interventions has led several investigators to develop means for ablating the atrioventricular (A V) node and/or bundle of His. In addition, the potential clinical utility of such a method has also been apparent (1, 2).


Ventricular Fibrillation Atrioventricular Block Complete Heart Block Versus Block Coronary Cusp 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Cobb FR, Blumenschein S, Sealy WC, Boineau JP, Wagner GS, Wallace AG: Successful surgical interruption of the bundle of Kent in a patient with Wolff-Parkinson-White syndrome. Circulation 1968; 38: 1018–1029.CrossRefPubMedGoogle Scholar
  2. 2.
    Dreifus LS, Nichols H, Morse D, Watanabe Y, Truex RC: Control of recurrent tachycardia of Wolff-Parkinson-White syndrome by surgical ligature of the A V bundle. Circulation 1968; 38: 1032–1036.CrossRefGoogle Scholar
  3. 3.
    Starz, TE, Gaertner RA: Chronic heart block in dogs. Method for producing experimental heart failure. Circulation 1955; 12: 259–270.CrossRefGoogle Scholar
  4. 4.
    Starzl, TE, Gaertner RA, Baker RR: Acute complete heart block in dogs. Circulation 1955; 12: 82–89.CrossRefPubMedPubMedCentralGoogle Scholar
  5. 5.
    Turina M, Babotai I, Wegmann W: Production of chronic atrioventricular blocks in dogs without thoracotomy. Cardiovasc Res 1968; 4: 389–393.CrossRefGoogle Scholar
  6. 6.
    Williams JCP, Lambert EH: Production of heart block in dogs without thoracotomy. Federation Proc 1964; 23: 413.Google Scholar
  7. 7.
    Steiner C, Kovalik AT: A simple technique for production of chronic complete heart block in dogs. J Appl Physiol 1968; 25: 631–632.PubMedGoogle Scholar
  8. 8.
    Babotai I, Brownlee R: Experimental atrioventricular block without thoracotomy: a new instrument. Cardiovasc Res 1971; 5: 416–418.CrossRefPubMedGoogle Scholar
  9. 9.
    Pruett JK, Woods EF. Technique for experimental complete heart block. J Appl Physiol 1967; 22: 830–831.PubMedGoogle Scholar
  10. 10.
    Wieberdink J: Experimental production of permanent heart block (total or bundle branch block) without circulatory arrest or extracorporeal circulation. Thorax 1966; 21: 401–404.CrossRefPubMedPubMedCentralGoogle Scholar
  11. 11.
    Klein GJ, Sealy WC, Pritchett EL, Harrison L, Hackel DB, Davis D, Kasell J, Wallace AG, Gallagher JJ: Cryosurgical ablation of the atrioventricular node-His bundle: Long-term follow-up and properties of the junctional pacemaker. Circulation 1980; 61: 8–15.CrossRefPubMedGoogle Scholar
  12. 12.
    Gonzalez R, Scheinman M, Margaretten W, Rubinstein M: Closed-chest electrodecatheter technique for His bundle ablation in dogs. Am J Physiol 1981; 241: H283–287.PubMedGoogle Scholar
  13. 13.
    Gallagher JJ, Svenson RH, Kasell JH, German LD, Bardy GH, Broughton A, Critelli G: Catheter technique for closed-chest ablation of the atrioventricular conduction system. A therapeutic alternative for the treatment of refractory supraventricular tachycardia. N Engl J Med 1982; 300: 194–200.CrossRefGoogle Scholar
  14. 14.
    Beazell JW, Adomian GE, Furmanski M, Tan KS: Experimental production of complete heart block by electrocoagulation in the closed chest dog. Am Heart J 1982; 104: 1328–1334.CrossRefPubMedGoogle Scholar
  15. 15.
    Gonzalez R, Scheinman M, Bharati S, Lev M: Closed chest permanent atrioventricular block in dogs. Am Heart J 1983; 105: 461–470.CrossRefPubMedGoogle Scholar

Copyright information

© Dr. Dietrich Steinkopff Verlag, GmbH & Co. KG, Darmstadt 1983

Authors and Affiliations

  • O.-J. Ohm
  • Leonard S. Dreifus
    • 1
  • H. Mitamura
  • Ch. Sauermelch
  • H. Haupt
  • S. Vail
  • M. Schaffenburg
  • E. L. Michelson
  1. 1.Lankenau HospitalPhiladelphiaUSA

Personalised recommendations