Use of Gelatins as Volume Expanders in Shock and Trauma
The most important function of the circulation is the transport of oxygen to the respiring tissues. Oxygen (O2) is the most vital of all the substrates carried by the circulation yet compared to the rate of utilisation it has the lowest stores and its consumption is also uniquely flow rather than consumption dependent. Lack of O2 does not only disrupt the function of the vital organs it may damage or completely destroy them. Therefore, the use of volume replacement theory in shock has to be considered in this context. The relationship between the delivery of oxygen (DO2) and oxygen consumption (VO2) is known as the oxygen transport (O2T) system. This is primarily considered in quantitative terms; normal values are summarised in Fig. 2.1.
KeywordsCardiac Index Acute Respiratory Distress Syndrome Central Venous Pressure Volume Expander Cardiogenic Shock
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