Immunological Basis of Pancreas Transplantation — Experimental Studies in the Rat

  • J. Klempnauer
  • H. Bektas
  • A. Jörns
  • W. F. A. Hiller


Histoincompatibility between donor and recipient forms the basis of allograft rejection. It is therefore a logical approach to minimize rejection of an allogenic transplant by tissue matching between donor and recipient for histocompatibility antigens. This procedure has been successful and is still applied in clinical kidney transplantation. Tissue typing, however, is not of primary importance in clinical liver or heart transplantation. The significance of tissue matching in clinical pancreas transplantation is still controversial.


Major Histocompatibility Complex Major Histocompatibility Complex Class Chronic Rejection Pancreas Transplantation Histocompatibility Antigen 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1998

Authors and Affiliations

  • J. Klempnauer
  • H. Bektas
  • A. Jörns
  • W. F. A. Hiller

There are no affiliations available

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