Immunological Basis of Pancreas Transplantation — Experimental Studies in the Rat
Histoincompatibility between donor and recipient forms the basis of allograft rejection. It is therefore a logical approach to minimize rejection of an allogenic transplant by tissue matching between donor and recipient for histocompatibility antigens. This procedure has been successful and is still applied in clinical kidney transplantation. Tissue typing, however, is not of primary importance in clinical liver or heart transplantation. The significance of tissue matching in clinical pancreas transplantation is still controversial.
KeywordsMajor Histocompatibility Complex Major Histocompatibility Complex Class Chronic Rejection Pancreas Transplantation Histocompatibility Antigen
Unable to display preview. Download preview PDF.
- 2.Klempnauer J, Settje A (1989) Vascularized pancreas transplantation in the rat — details of the microsurgical techniques, results, and complications. Transplant Int 2:84–91Google Scholar