Abstract
Acute deterioration in the gastrointestinal (GI) mucosa was first recognized in critically ill patients approximately 25 years ago. At that time gastric endoscopy demonstrated that between 80-100% of patients would have acute mucosal damage within 24 hrs of admission [1,2]. The term “stress-related” was borne. Bleeding at that time was not common, but if it occurred, mortality rates as high as 80% were reported [1]. Even at that time certain subsets of patients were thought to be more at risk. These included patients with severe burns, head injuries, circulatory shock, respiratory failure, sepsis and multiple organ failure [1,3]. Some pathologic states had specific names given to the associated acute upper GI mucosal changes such as Cushing’s ulcers in patients with intracranial pathology [4].
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Eddleston, J. (1998). Stress Ulceration in the Critically III Population. In: Vincent, JL. (eds) Yearbook of Intensive Care and Emergency Medicine 1998. Yearbook of Intensive Care and Emergency Medicine, vol 1998. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-72038-3_56
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DOI: https://doi.org/10.1007/978-3-642-72038-3_56
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