Icosanoids, Chromosome Damage and Cancer
A relationship between chromosome damage and cancer is documented by the observation that agents known for their carcinogenic properties, such as ionizing radiation, certain viruses and many chemicals, induce chromosome damage. Three hereditary diseases, the congenital breakage syndromes, combine chromosome instability with a high risk of developing malignancy. They therefore represent another example of the association of chromosome damage and cancer.
KeywordsEnzymatic Degradation Prostaglandin Catalase Indomethacin PGE2
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