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Amino Acid Metabolism in Brain Tumors

  • Conference paper
Book cover Regulation of Cerebral Blood Flow and Metabolism Neurosurgical Treatment of Epilepsy Rehabilitation in Neurosurgery

Part of the book series: Advances in Neurosurgery ((NEURO,volume 15))

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Abstract

Positron emission tomography (Pet) has become the most sophisticated method for studying regional metabolic functions of the brain (PHELPS 1986; REIVICH and ALAVI 1986). While blood flow, glucose consumption, and receptor densities are all highly structured, with active centers in normal and in pathological conditions, other functions, like oxygen extraction and protein synthesis, show a more uniform distribution in normal physiological situations (Frackowiak and Lammertsma 1985). However, oxygen extraction is a high level process in brain tissue, whereas protein synthesis is low in normal brain. Therefore increased protein synthesis in pathological states may be an ideal indicator, with high contrast for abnormally growing tissue in the brain.

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Author information

Authors and Affiliations

  1. Abteilung Nuklearmedizin und spezielle Biophysik, Medizinische Hochschule Hannover, Konstanty-Gutschow-Straße 8, D-3000, Hannover 61, Germany

    O. Schober, G.-J. Meyer, M. R. Gaab, J.-A. Müller, E. Rickels, H. Dietz & H. Hundeshagen

Authors
  1. O. Schober
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  2. G.-J. Meyer
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  3. M. R. Gaab
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  4. J.-A. Müller
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  5. E. Rickels
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  6. H. Dietz
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  7. H. Hundeshagen
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Editor information

Editors and Affiliations

  1. Neurochirurgische Universitäts-Klinik Bonn, Sigmund-Freud-Straße 25, D-5300, Bonn 1, Germany

    Rolf Wüllenweber

  2. Neurochirurgische Klinik der Universität Erlangen-Nürnberg, Schwabachanlage 6 (Kopfklinikum), D-8520, Erlangen, Germany

    Margareta Klinger

  3. Neurochirurgische Klinik und Poliklinik Universitätsklinikum Steglitz, Freie Universität Berlin, Hindenburgdamm 30, D-1000, Berlin 45, Germany

    Mario Brock

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© 1987 Springer-Verlag Berlin Heidelberg

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Schober, O. et al. (1987). Amino Acid Metabolism in Brain Tumors. In: Wüllenweber, R., Klinger, M., Brock, M. (eds) Regulation of Cerebral Blood Flow and Metabolism Neurosurgical Treatment of Epilepsy Rehabilitation in Neurosurgery. Advances in Neurosurgery, vol 15. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71793-2_21

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  • DOI: https://doi.org/10.1007/978-3-642-71793-2_21

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-17402-8

  • Online ISBN: 978-3-642-71793-2

  • eBook Packages: Springer Book Archive

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