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Improvement of Cerebral Blood Flow in Acute Ischemia of the Brain

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Regulation of Cerebral Blood Flow and Metabolism Neurosurgical Treatment of Epilepsy Rehabilitation in Neurosurgery

Part of the book series: Advances in Neurosurgery ((NEURO,volume 15))

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Abstract

The most appropriate therapy for acute cerebral ischemia is still a matter of debate. Attempts at vasodilation by hypercapnia (14a), pharmacological vasodilatation (16), and barbiturate protection (17) have not gained general acceptance:

  • Hypercapnia and administration of cerebral vasodilators may cause steal effects, so decreasing flow in the tissue of concern. Hyperventilation with consecutive vasoconstriction may cause an increase of flow in the ischemic tissue if vasoparalysis has taken place. However, in the neighborhood with reacting vessels, blood flow may be at a critical level which during hypocapnia leads to further flow depression and provocation of true ischemia.

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Authors and Affiliations

  1. Neurologische Universitätsklinik, Sigmund-Freud-Straße 25, D-5300, Bonn 1, Germany

    A. Hartmann

Authors
  1. A. Hartmann
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Editors and Affiliations

  1. Neurochirurgische Universitäts-Klinik Bonn, Sigmund-Freud-Straße 25, D-5300, Bonn 1, Germany

    Rolf Wüllenweber

  2. Neurochirurgische Klinik der Universität Erlangen-Nürnberg, Schwabachanlage 6 (Kopfklinikum), D-8520, Erlangen, Germany

    Margareta Klinger

  3. Neurochirurgische Klinik und Poliklinik Universitätsklinikum Steglitz, Freie Universität Berlin, Hindenburgdamm 30, D-1000, Berlin 45, Germany

    Mario Brock

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© 1987 Springer-Verlag Berlin Heidelberg

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Hartmann, A. (1987). Improvement of Cerebral Blood Flow in Acute Ischemia of the Brain. In: Wüllenweber, R., Klinger, M., Brock, M. (eds) Regulation of Cerebral Blood Flow and Metabolism Neurosurgical Treatment of Epilepsy Rehabilitation in Neurosurgery. Advances in Neurosurgery, vol 15. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71793-2_14

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  • DOI: https://doi.org/10.1007/978-3-642-71793-2_14

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-17402-8

  • Online ISBN: 978-3-642-71793-2

  • eBook Packages: Springer Book Archive

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