Abstract
Interest in the specific effects of individual fatty acids on the pathogenesis of coronary heart disease (CHD) has been limited. There are a number of reasons for this. They include (1) the fact that the whole field of CHD has been dominated for years by cholesterol metabolism, (2) the indication from cross-cultural surveys of food habits that there are strong relationships between dietary saturated fat (as a whole) and serum cholesterol, on the one hand, and age-standardised 5-year CHD rates, on the other [1], and (3) the fact that virtually all polyunsaturated fatty acids have quite a profound effect in lowering plasma cholesterol and low-density lipoprotein (LDL) cholesterol, and this has come to be regarded as an adequate end in itself because of the presumed but unproven benefit which populations and individuals (with the exception of those with very high levels) may obtain from reduction of raised serum and LDL cholesterol.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Keys A (1970) Coronary heart disease in seven countries. American Heart Association Monograph 29
Logan RL, Thomson M, Riemersma RA et al. (1978) Risk factors for ischaemic heart disease in normal men aged 40. Lancet i: 949–955
Riemersma RA, Wood DA, Butler S et al. (1986) Linoleic acid in adipose tissue and coronary heart disease. Br Med J 292: 1423–1427
Wood DA, Butler S, Riemersma RA et al. (1984) Adipose tissue and platelet fatty acids and coronary heart disease in Scottish men. Lancet 11: 117–121.
Van Staveren WA, Deurenberg P, Katan MB, et al. (1986) Validity of the fatty acid composition of subcutaneous fat tissue microbiopsies as an estimate of the long term average fatty acid composition of the diet of separate individuals. Am J Epidemiol 123: 455–463
Wood DA, Riemersma RA, Butler S et al. (1987) Linoleic and eicosapentaenoic acids in adipose tissue and platelets and risk of coronary heart disease. Lancet i: 177–183
Thomson M, Fulton M, Wood DA et al. (1985) A comparison of the nutrient intake of some Scotsmen with dietary recommendations. Hum Nutr Appl Nutr 39 A: 443–455
Ahrens EH, Insull W, Hirsch J et al. (1959) The effect on human serum-lipids of a dietary fat, highly unsaturated, but poor in essential fatty acids. Lancet i: 115
Phillipson BE, Rothrock DW, Connor WE et al. (1985) Reduction of plasma lipids, lipoproteins and apoproteins by dietary fish oils in patients with hypertriglyceridemia. N Engl J Med 312: 1210–1216
Dyerberg J, Bang HO (1979) Haemostatic function and platelet polyunsaturated fatty acids in Eskimos. Lancet i: 433–435
Kromhout D, Bosschieter EB, Coulander C de L (1985) The inverse relation between fish consumption and 20-year mortality from coronary heart disease. N Engl J Med 312: 1205–1209
Shekelle RB, Paul O, Stamler J (1985) Fish consumption and mortality from coronary heart disease. N Engl J Med 313: 820
Vollset SE, Heuch I, Bjelke E (1985) Fish consumption and mortality from coronary heart disease. N Engl J Med 313: 821
Curb JD, Reed DM (1985) Fish consumption and mortality from coronary heart disease. N Engl J Med 313: 821
Puska P, Iacono JM, Nissinen A et al. (1983) Controlled randomised trial of the effect of dietary fat on blood pressure. Lancet i: 1–5
Knapp HR, Reilly IAG, Alessandrini P et al. (1986) In vivo indexes of platelet and vascular function during fish-oil administration in patients with atherosclerosis. N Engl J Med 314: 937–942
Grundy SM (1986) Comparison of monounsaturated fatty acids and carbohydrates for lowering plasma cholesterol. N Engl J Med 314: 745–748
Miettinen TA, Naukkarinen V, Huttunen JK et al. (1982) Fatty-acid composition of serum lipids predicts myocardial infarction. Br Med J 285: 993–996
Heagerty AM, Ollerenshaw JD, Robertson DI et al. (1986) Influence of dietary linoleic acid on leucocyte sodium transport and blood pressure. Br Med J 293: 295–297
Berry EM, Hirsch J (1986) Does dietary linoleic acid influence blood pressure? Am J Clin Nutr 44: 336–340
Dyerberg J, Bang HO (1979) Haemostatic function and platelet polyunsaturated fatty acids in Eskimos. Lancet ii: 433–435
Kirkeby K, Ingvaldsen P, Bjerkedal I (1972) Fatty acid composition of serum lipids in men with myocardial infarction. Acta Med Scand 192: 513–519
Gudbjarnason S, Hallgrimsson J (1979) In: Hayase S, Murao S (eds) Proceedings of the VIII world congress of cardiology, Tokyo, 17–23 September 1978. Excerpta Medica, Amsterdam pp 245–247 (International Congress Series No.470)
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1987 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Oliver, M.F. (1987). Essential Fatty Acids, Marine Oils, Olive Oil and Coronary Heart Disease. In: Schlierf, G., Mörl, H. (eds) Expanding Horizons in Atherosclerosis Research. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71753-6_39
Download citation
DOI: https://doi.org/10.1007/978-3-642-71753-6_39
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-71755-0
Online ISBN: 978-3-642-71753-6
eBook Packages: Springer Book Archive