Arenaviruses pp 131-143 | Cite as

Nature of the Inflammatory Process in the Central Nervous System of Mice Infected with Lymphocytic Choriomeningitis Virus

  • J. E. Allan
  • J. E. Dixon
  • P. C. Doherty
Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 134)

Abstract

Lymphocytic choriomeningitis (LCM) is an inflammatory disease that occurs in immunologically competent adult mice after infection of the brain with LCM virus (LCMV). Tremors develop in the legs, head, and tail, and characteristic extensor spasms of the hind legs are found during the terminal stage of disease, usually within 1 week of infection.

Keywords

Lymphoma Influenza Neurol Cyclophosphamide Meningitis 

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Copyright information

© Springer-Verlag Berlin · Heidelberg 1987

Authors and Affiliations

  • J. E. Allan
    • 1
  • J. E. Dixon
    • 1
  • P. C. Doherty
    • 1
  1. 1.Department of Experimental Pathology, John Curtin School of Medical ResearchAustralian National UniversityCanberra CityAustralia

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