Zusammenfassung
Da bei AIDS-Erkrankten bestimmte anteilmäßige Veränderungen der Lympho zytensubpopulationen sowie der Lymphozytenstimulierbarkeit festgestellt worden waren [1–3], haben wir die Immunitätslage von substituierten und nicht substituierten Kindern mit Hämophilie A, Hemmkörperhämophilie und mit von Willebrand-Syndrom untersucht und mit den Werten des Kontrollkollektivs verglichen.
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Literatur
Center for Disease Control (1982) Immunodeficiency among female sexual partners of males with acquired immune deficiency syndrome (AIDS). Morbid Mortal Weekly Rep 31:697
Rubinstein A, Sicklick M, Gupta A, Bernstein L, Klein N, Rubinstein E, Spigland I, Fruchter L, Litman N, Lee H, Holländer M (1983) Acquired immunodeficiency with reversed T4/T8 ratios in infants born to promiscuous and drug-addicted mothers. JAMA 249:2350
Ciobanu N, Weite K, Kruger G, Venuta S, Gold J, Feldmann SP, Wang CY, Koziner B, Moore MAS, Safai B, Mertelsmann R (1983) Defective T-cell response to PHA and mitogenic monoclonal antibodies in male homosexuals with acquired immunodeficiency syndrome and its in vitro correction by interleukin 2. J Clin Immunol 3:332
Chang TW, Kung PC, Gingras SP, Goldstein G (1981) Does OKT3 monoclonal antibody react with an antigen-recognition structure on human T-cell? Proc Natl Acad Sci 78:1805
Reinherz EL, Meuer S, Fitzgerald KA, Hussey RE, Levine H, Schlossmann SF (1982) Antigen recognition by human T-lymphocytes is linked to surface expression of the T3 molecular couples. Cell 30:735
Weite K, Wang Y, Mertelsmann R, Venuta S, Feldmann SP, Moore MAS (1982) Purification of human interleukin-2 to apparent homogeneity and its molecular heterogeneity. J Exp Med 156:454
Weite K, Ciobanu N, Kruger G, Venuta S, Feldmann SP, Sternberg C, Palladino MA, Koziner B, Gold J, Safai B, Moore MAS, Oettgen HF, Mertelsmann R (1983) Impaired interleukin-2 production in response to PHA and OKT3 antibody in male homosexuals with acquired immune deficiency syndrome: In vitro restoration of T-cell proliferation by highly purified interleukin-2. In: AIDS: Friedman-Kien AE, Laubenstein LJ (eds). The epidemic of Kaposi’s sarcoma and opportunistic infections. Masson Inc New York NY
Weite K, Venuto S, Wang CY, Feldmann SP, Ciobanu N, Kruger G, Feickert HJ, Merluzzi VJ, Flomenberg N, Moore MAS, Mertelsmann R (1983) Human interleukin-2: Physiology, biochemistry and pathophysiology in lymphoblastic leukemias and immunodeficiency syndromes. Haematol Blood Transf 28:369
Brackmann HH, Gormsen J (1977) Massive factor VIII infusion in haemophiliac patient with factor VIII inhibitor, high responder. Lancet
Kreuz W, Scharrer I (1984) Elimination of factor VIII inhibitors in 6 children with severe hemophilia A. XVI International congress of the world federation of hemophilia. Rio de Janeiro, Brazil. Books of Abstracts
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© 1986 Springer-Verlag Berlin Heidelberg
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Kreuz, W., Ebener, U., Kornhuber, B. (1986). Einfluß von Human-Interleukin-2 auf die zelluläre Immunität bei Hämophilie A- und von Willebrand-Patienten im Kindesalter. In: Landbeck, G., Marx, R. (eds) 2. Rundtischgespräch Therapiebedingte Infektionen und Immundefekte bei Hämophilen. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71664-5_18
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DOI: https://doi.org/10.1007/978-3-642-71664-5_18
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