Skip to main content
SpringerLink
Log in

Ontogeny of the Secretory Elements in the Vertebrate Olfactory Mucosa

  • Chapter
Book cover Ontogeny of Olfaction

Abstract

The olfactory mucosa of vertebrates contains secretory elements that produce a layer of mucus that covers the surface of the olfactory epithelium (Graziadei 1971; Yamamoto 1982). The secretions presumably play a role in olfactory function by (a) providing the ionic and macromolecular environment in which odorants interact with their receptor sites on the olfactory receptor neurons (Bannister 1974; TV Cetchell and ML Getchell 1977), (b) affecting access of odorants to the epithelial surface (Mozell 1971; Bostock 1974) and (c) facilitating odorant removal (Hornung and Mozell 1981; TV Getchell et al. 1985).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Bakhtin YK (1976) Morphology of the olfactory organ of some fish species and a possible functional interpretation. J Ichthyol 16: 786–804

    Google Scholar 

  • Bang BG (1964) The mucous glands of the developing human nose. Acta Anat 59: 297–314

    Article  CAS  PubMed  Google Scholar 

  • Bannister LK (1974) Possible functions of mucus at gustatory and olfactory surfaces. In: Poynder TM (ed) Transduction mechanisms in chemoreception. IRL Press, London, pp 39–46

    Google Scholar 

  • Bertmar C (1973) Ultrastructure of the olfactory mucosa in the homing Baltic Sea trout Salmo trutta trutta. Mar Biol 19: 74–88

    Article  Google Scholar 

  • Bostoch H (1974) Diffusion and the frog EOG. In: Poynder TM (ed) Transduction mechanisms in chemoreception. IRL Press, London, pp 27–38

    Google Scholar 

  • Breipohl W (1972) Licht- und elektronenmikroskopische Befunde zur Struktur der Bowmanschen Drüsen in Riechepithel der weißen Maus. Z Zellforsch 131: 329–346

    Article  CAS  PubMed  Google Scholar 

  • Breipohl W, Fernandez M (1977) Scanning electron microscopic investigations of olfactory epithelium in the chick embryo. Cell Tissue Res 183: 105–114

    Article  CAS  PubMed  Google Scholar 

  • Breipohl W, Bijvank GJ, Zippel HP (1973a) Die Oberflächenstruktur der olfaktorischen Drüsen des Goldfisches (Carassius auratus). Eine rastermikroskopische Studie. Z Zellforsch 140: 567–582

    Article  CAS  PubMed  Google Scholar 

  • Breipohl W, Mestres P, Meller K (1973b) Licht- und elektronenmikroskopische Befunde zur Differenzierung des Riechepithels der weißen Maus. Verh Anat Ges 67: 443–449

    Google Scholar 

  • Breipohl W, Moulton D, Ummels M, Matulionis DH (1982) Spatial pattern of sensory cell terminals in the olfactory sac of the tiger salamander. I. A scanning electron microscope study. J. Anat 134: 757–769

    CAS  PubMed  Google Scholar 

  • Bücher U, Reid L (1961) Development of the mucus-secreting elements in human lung. Thorax 16: 219–225

    Article  PubMed  Google Scholar 

  • Cuschieri A, Bannister LH (1975a) The development of the olfactory mucosa in the mouse: light microscopy. J Anat 119: 277–286

    CAS  PubMed  Google Scholar 

  • Cuschieri A, Bannister LH (1975b) The development of the olfactory mucosa in the mouse: electron microscopy. J Anat 119: 471–498

    CAS  PubMed  Google Scholar 

  • Filyushina YY, Bakhmin YK (1975) Electron-microscopic investigation of the olfactory epithelium of the Baikal omul Coregonus autumnalis migratorius. J Ichthyol 15: 284–290

    Google Scholar 

  • Getchell ML, Getchell TV (1984a) β-Adrenergic regulation of the secretory granule content of acinar cells in olfactory glands of the slamander. J Comp Physiol A 155: 435–443

    Article  CAS  Google Scholar 

  • Getchell ML, Getchell TV (1984b) Cholinergic control of glandular secretion in the olfactory mucosa of the salamander. In: Abstr Proc Annu Meet Assoc Chemoreception Sci, Sarasota, FL

    Google Scholar 

  • Getchell ML, Rafols JA, Getchell TV (1984) Histological and histochemical studies of the secretory components of the salamander olfactory mucosa: Effects of isoproterenol and olfactory nerve section. Anat Rec 208: 553–565

    Article  CAS  PubMed  Google Scholar 

  • Getchell TV (1977) Analysis of intracellular recordings from salamander olfactory epithelium. Brain Res 123: 275–286

    Article  CAS  PubMed  Google Scholar 

  • Getchell TV, Getchell ML (1977) Histochemical localization and identification of secretory products in salamander olfactory epithelium. In: LeMagnen J, MacLeod P (eds) Olfaction and taste, vol VI. IRL Press, London, pp 105–112

    Google Scholar 

  • Getchell TV, Zielinski B, Getchell ML (1985) Pyrazine-mediated neural and secretory activity in the olfactory mucosa of the salamander (abstr). Chem Sens 10: 398

    Google Scholar 

  • Graziadei PPC (1971) The olfactory mucosa of vertebrates. In: Beidler LM (ed) Handbook of sensory physiology, vol IV. Chemical senses 1. Olfaction. Springer, Berlin Heidelberg New York, pp 27–58

    Google Scholar 

  • Graziadei PPC, Monti Graziadei GA (1976) Olfactory epithelium of Necturus maculosus and Ambystoma tigrinum. J Neurocytol 5: 11–32

    Article  CAS  PubMed  Google Scholar 

  • Hafez ESE (1977) Functional anatomy of mucus-secreting cells. In: Elstein M, Parke DV (eds) Mucus in health and disease. Plenum Press, New York, pp 19–34

    Google Scholar 

  • Herberhold C (1968) Vergleichende histochemische Untersuchungen am peripheren Riechorgan von Säugetieren und Fischen. Arch Klin Exp Ohr Nas Kehlk Heilkd 190: 166–182

    Article  CAS  Google Scholar 

  • Hornung DE, Mozell MM (1981) Accessibility of odorant molecules to the receptors. In: Cagan RH, Kare MR (eds) Biochemistry of taste and olfaction. Academic Press, London New York, pp 33–45

    Google Scholar 

  • Kauer JS (1981) Olfactory receptor cell staining using horseradish peroxidase. Anat Rec 200: 331–336

    Article  CAS  PubMed  Google Scholar 

  • Kleerekoper H (1969) Olfaction in Fishes. Indiana Univ Press, Bloomington

    Google Scholar 

  • Klein SL, Graziadei PPC (1983) The differentiation of the olfactory placode in Xenopus laevis: a light and electron microscope study. J Comp Neurol 217: 17–30

    Article  CAS  PubMed  Google Scholar 

  • Masukawa LM, Kauer JS, Shepherd GM (1983) Intracellular recordings from two cell types in an in vitro preparation of the salamander olfactory epithelium. Neurosci Lett 35: 59–64

    Article  CAS  PubMed  Google Scholar 

  • Masukawa LM, Hedlund B, Shepherd GM (1985a) Electrophysiological properties of identified cells in the in vitro olfactory epithelium of the tiger salamander. J Neurosci 5: 128–135

    CAS  PubMed  Google Scholar 

  • Masukawa LM, Hedlund B, Shepherd GM (1985b) Changes in the electrical properties of olfactory epithelial cells in the tiger salamander after olfactory nerve transection. J Neurosci 5: 136–141

    CAS  PubMed  Google Scholar 

  • Mozell MM (1971) Spatial and temporal patterning. In: Beidler LM (ed) Handbook of sensory physiology, vol IV. Chemical senses 1. Olfaction. Sringer, Berlin Heidelberg New York, pp 205–215

    Google Scholar 

  • Ojha PP, Kapoor AS (1972) Histochemistry of the olfactory epithelium of the fish, Canna punctatus Bloch. Acta Anat 83: 540–555

    Article  CAS  PubMed  Google Scholar 

  • Okano M, Takagi SF (1974) Secretion and electrogenesis of the supporting cell in the olfactory epithelium. J Physiol (London) 242: 353–370

    CAS  Google Scholar 

  • Pyatkina CA (1982) Development of the olfactory epithelium in man. Z Mikrosk Anat Forsch Leibzig 96: 361–372

    CAS  Google Scholar 

  • Rafols JA, Getchell TV (1983) Morphological relations between the receptor neurons, sustentacular cells and Schwann cells in the olfactory mucosa of the salamander. Anat Rec 206: 87–101

    Article  CAS  PubMed  Google Scholar 

  • Scifert K (1971) Licht- und elektronenmikroskopische Untersuchungen der Bowman-Drüsen in der Riechschleimhaut makrosmatischer Säuger. Arch Klin Exp Ohr Nas Kehlk Heilkd 200: 252–274

    Article  Google Scholar 

  • Simmons PA, Rafols JA, Getchell TV (1981) Ultrastructural changes in olfactory receptor neurons following olfactory nerve section. J Comp Neurol 197: 237–257

    Article  CAS  PubMed  Google Scholar 

  • Spicer SS, Chakrin LW, Wardell JR Jr, Kendrick W (1971) Histochemistry of mucosubstances in the canine and human respiratory tract. Lab Invest 25: 483–490

    CAS  PubMed  Google Scholar 

  • Thaete LG, Spicer SS, Spock A (1981) Histology, ultrastructure, and carbohydrate cytochemistry of surface and glandular epithelium of human nasal mucosa. Am J Anat 162: 243–263

    Article  CAS  PubMed  Google Scholar 

  • Theisen B, Breucker H, Zeiske E, Melinkat R (1980) Structure and development of the olfactory organ in the garfish Belone belone (L.) (Teleostei, Atheriniformes) Acta Zool (Stockholm) 61: 161–170

    Google Scholar 

  • Tos M (1982) Goblet cells and glands in the nose and paranasal sinuses. In: Proctor DF, Andersen I (eds) The nose. Upper airway physiology and the atmospheric environment. Elsevier Biomedical Press, Amsterdam New York Oxford, p 99

    Google Scholar 

  • Tos M, Poulsen J (1975) Mucous glands in the developing human nose. Arch Otolaryngol 101: 367–372

    CAS  PubMed  Google Scholar 

  • Trotier D, MacLeod P (1983) Intracellular recordings from salamander olfactory cells. Brain Res 268: 225–237

    Article  CAS  PubMed  Google Scholar 

  • Yamamoto M (1982) Comparative morphology of the peripheral olfactory organ in teleosts. In: Hara TJ (ed) Chemoreception in fishes. Elsevier, Amsterdam, pp 39–59

    Google Scholar 

  • Zeiske E, Melinkat R, Breucker H, Kux J (1976) Ultrastructural studies of the epithelia of the olfactory organ of cyprinodonts (Teleostei, Cyprinodontoidea). Cell Tissue Res 172: 245–267

    Article  CAS  PubMed  Google Scholar 

  • Zielinski B (1985) Morphological and physiological studies of the development of the peripheral olfactory organ in rainbow trout, Salmo gairdneri. Thesis, Univ. Manitoba, Winnipeg

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Anatomy and Cell Biology, Wayne State University School of Medicine, Detroit, Michigan, 48201, USA

    M. L. Getchell, B. Zielinski & T. V. Getchell

Authors
  1. M. L. Getchell
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. B. Zielinski
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. T. V. Getchell
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Department of Anatomy, University of Queensland, St. Lucia/Brisbane, Australia, 4067

    Winrich Breipohl

  2. Institut für Biologie III, Universität Tübingen, 7400, Tübingen, Germany

    Raimund Apfelbach

Rights and permissions

Reprints and permissions

Copyright information

© 1986 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Getchell, M.L., Zielinski, B., Getchell, T.V. (1986). Ontogeny of the Secretory Elements in the Vertebrate Olfactory Mucosa. In: Breipohl, W., Apfelbach, R. (eds) Ontogeny of Olfaction. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71576-1_6

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-71576-1_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-71578-5

  • Online ISBN: 978-3-642-71576-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation