Zusammenfassung
Hormone sind chemische Verbindungen, die in speziellen Drüsen oder Zellverbänden synthetisiert und an den Blutkreislauf abgegeben werden. Sie dienen als Informationsträger und veranlassen in ihren Zielorganen eine physiologische Wirkung. Charakteristisch für die Hormone ist, daß sie ihre Wirkungen mit sehr hoher Spezifität ausüben und daß für ihre Wirkung nur sehr niedrige Konzentrationen nötig sind. Diese Spezifität und Empfindlichkeit wird durch die Hormonrezeptoren gewährleistet, die im Zielgewebe die Signale der Hormone selektiv erkennen und verarbeiten. Die Reaktion eines Hormones mit seinem Rezeptor löst im entsprechenden Zielorgan eine Stoffwechselwirkung aus. Die entstehenden Stoffwechselprodukte üben ihrerseits wieder einen regulativen Einfluß auf die Hormonproduktion aus. Dieser Effekt wird als Rückkopplung (Feedback) bezeichnet. Zwischen Hypothalamus, Hypophysenvorderlappen und verschiedenen Erfolgsorganen wie Nebennierenrinde, Schilddrüse und Ovar bestehen solche sich selbst steuernde Regelkreise.
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Klinga, K. (1987). Hormone. In: Gynäkologische Endokrinologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71568-6_1
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