Abstract
Motor neuron disease, or amyotrophic lateral sclerosis (ALS) is by no means uncommon. The number of new cases per year is more than half that reported for multiple sclerosis although the prevalence is low because of the rapid and fatal course of the disease. It is — and has been for the last 100 years — a major challenge to the neurologist to search for the cause and for an effective treatment of this disease. Despite the prominent symptoms such as progressive generalized paresis in striated muscle, the neuronal damage responsible for paresis is far from generalized, as it is concentrated in lower motor neurons in the spinal cord and brain stem and in neurons in descending tracts of the spinal cord, especially in the pyramidal tract.
Keywords
- Amyotrophic Lateral Sclerosis
- Motor Neuron
- Amyotrophic Lateral Sclerosis Patient
- Motor Neuron Disease
- Lower Motor Neuron
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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© 1987 Springer-Verlag Berlin Heidelberg
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Conradi, S. (1987). Functional Implications of Structure and Synaptology of Motor Neurons in Motor Neuron Disease. In: Struppler, A., Weindl, A. (eds) Clinical Aspects of Sensory Motor Integration. Advances in Applied Neurological Sciences, vol 4. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71540-2_10
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DOI: https://doi.org/10.1007/978-3-642-71540-2_10
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