Desensitization of Iloprost or Prostacyclin Responsiveness
The biological effects of prostacyclin (PGI2) are mediated by activation of adenylate cyclase. In most respects the biochemical events that accompany occupation by agonist of specific PGI2 receptors on “target tissues” are similar to those described for numerous other neurotransmitter and hormonal systems.
KeywordsAdenylate Cyclase Fractional Occupancy Royal Postgraduate Medical School Prostacyclin Receptor Nylate Cyclase
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