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Quaternary Structure and Modulation of Function in Earthworm Erythrocruorin

  • E. Chiancone
  • F. Ascoli
  • B. Giardina
  • R. Santucci
  • P. Vecchini
  • D. Verzili
Conference paper

Abstract

In the study of the structural and functional properties of erythrocruorins one of the most interesting aspects regards the elucidation of the reciprocal effects arising from the interplay of protons, monovalent and divalent cations. It may be recalled that erythrocruorins are characterized by a complex hierarchical quaternary structure. Thus, in the electron microscope the native molecule appears as an hexagonal bilayer with an apparently empty central cavity, each layer consisting of six subunits; in turn the 1/12 subunits are formed by three or four lower molecular weight ones (1,2). However, the detailed arrangement of the constituent polypeptide chains in the subunits appearing in the electron microscope is still elusive.

Keywords

Divalent Cation Quaternary Structure Oxygen Affinity Calcium Binding Site Native Molecule 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1986

Authors and Affiliations

  • E. Chiancone
    • 1
    • 2
  • F. Ascoli
    • 1
    • 2
  • B. Giardina
    • 1
    • 2
  • R. Santucci
    • 1
    • 2
  • P. Vecchini
    • 1
    • 2
  • D. Verzili
    • 1
    • 2
  1. 1.CNR Center of Molecular Biology, Institutes of Chemistry and BiochemistryUniversity of Rome ‘La Sapienza’Italy
  2. 2.Department of Cell BiologyUniversity of CamerinoItaly

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