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Morphology of Hypothalamus and Its Connections pp 1–47Cite as

The Pituitary Portal System

  • Conference paper

Part of the book series: Current Topics in Neuroendocrinology ((CT NEUROENDOCRI,volume 7))

Abstract

By 1970, the picture seemed to be complete. Wislocki and King (1936) had first accurately described the portal system in 1936 after injecting monkeys, cats, and rabbits with India ink. They reported that superior hypophyseal arteries supplied the capillary bed of the median eminence. Its capillaries coalesced into long portal “venules” which passed between the median eminence and the pars distalis, where they then arborized into a secondary capillary bed. These capillaries in turn coalesced into lateral and inferior hypophyseal veins, which passed to the adjacent cavernous sinus. E. Scharrer and B. Scharrer (1940, 1944) had proposed the concept of neurosecretion, and ample evidence was forthcoming to support it as the means by which the brain controls posterior pituitary (neural lobe) function (Verney 1947; Vigneaud et al. 1953; VanDyke 1955; Palay 1955, 1960; Sloper et al. 1960; Bargmann 1966).

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  1. Milton S. Hershey Medical Center, The Pennsylvania State University, P. O. Box 850, Hershey, PA, 17033, USA

    R. B. Page

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  1. Pharmakologisches Institut, Universität Heidelberg, Im Neuenheimer Feld 366, 6900, Heidelberg, Germany

    Detlev Ganten M.D., Ph.D.

  2. Rockefeller University, York Avenue, and 66th Street, New York, NY, 10021, USA

    Donald Pfaff Ph.D.

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Page, R.B. (1986). The Pituitary Portal System. In: Ganten, D., Pfaff, D. (eds) Morphology of Hypothalamus and Its Connections. Current Topics in Neuroendocrinology, vol 7. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71461-0_1

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