Synthetic Study of Natural Products Via Three-Membered Heterocycles
The outstanding characteristic of the three-membered hetero rings is their high reactivity to a wide variety of reagents because of the favorable release of strain energy involved. For this reason, these heterocycles may be converted to a wide variety of functiona-lized compounds by nucleophilic or electrophilic ring openings. In this symposium, I will mention syntheses of alkaloids, terpenes and β-lactam antibiotics, in which the reaction of a tentatively formed or an easily available three-membered heterocycles becomes the key step in a formation of the basic skeleton of natural products.
KeywordsSodium Borohydride Total Synthesis Rose Bengal Raney Nickel Isoquinoline Alkaloid
Unable to display preview. Download preview PDF.
- 1.T. Kametani, T. Ohsawa, and M. Ihara, J. Chem. Soc. Perkin I, 1981, 1563.Google Scholar
- 7.T. Kametani, K. Suzuki, H. Kurobe, and H. Nemoto, Chem. and Pharm. Bull. (Japan), 1981, 29, 105.Google Scholar
- 14.K. Higashiyama, T. Honda, H. Otomasu, and T. Kametani, Planta medica, 1983, 268.Google Scholar
- 15.T. Kametani, K. Higashiyama, T. Honda, and H. Otomasu, Heterocycles, in press.Google Scholar
- 16.T. Kametani, K. Higashiyama, T. Honda, and H. Otomasu, Chem. and Pharm. Bull (Japan), in press.Google Scholar
- 17.T. Kametani, K. Hiagshiyama, H. Otomasu, and T. Honda, Heterocycles, in press.Google Scholar