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Experimental and Clinical Use of Tisseel (Tissucol) and Muscle to Reinforce Rat Arteries and Human Cerebral Saccular Aneurysms

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Fibrin Sealant in Operative Medicine
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Abstract

Muscle wrapping of cerebral saccular aneurysms has been used since 1933. It seems that a gap always occurs between the muscle and the aneurysm wall and therefore the method of muscle wrapping has not found widespread use. In a rat model we have used rat-Tisseel to produce an immediate effective contact between pieces of muscle and the rat femoral artery wall, confirmed by histological examinations up to 1 month postoperatively. The use of Tisseel in human cases of muscle wrapping of giant aneurysms or broad-based, nonclippable aneurysms is introduced.

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© 1986 Springer-Verlag Berlin Heidelberg

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Haase, J., Falk, E., Madsen, F.F., Teglbjærg, P.S. (1986). Experimental and Clinical Use of Tisseel (Tissucol) and Muscle to Reinforce Rat Arteries and Human Cerebral Saccular Aneurysms. In: Schlag, G., Redl, H. (eds) Fibrin Sealant in Operative Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71391-0_24

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  • DOI: https://doi.org/10.1007/978-3-642-71391-0_24

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-16828-7

  • Online ISBN: 978-3-642-71391-0

  • eBook Packages: Springer Book Archive

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