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Neural Tissue Transplants Modify Response of the Immature Spinal Cord to Damage

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Book cover Glial-Neuronal Communication in Development and Regeneration

Part of the book series: NATO ASI Series ((ASIH,volume 2))

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Abstract

Neural tissue transplantation techniques have been used extensively in recent years to examine questions concerning development and regeneration in the developing and mature central nervous system (see 1,2,3, for reviews). For example, transplants derived from various levels of the neuraxis survive, grow, and differentiate when placed into cavities or lesions in the adult or newborn nervous system (4–13). Often anatomical projections between host and transplant tissue are established. In some instances, the transplants are able to mediate recovery of function after CNS lesions either by establishing axonal connections with the host nervous system or by releasing hormones or neurotransmitters which are able to act on neurons within the host (3, 7, 14-19).

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Authors and Affiliations

  1. Department of Anatomy, University of Maryland School of Medicine, Baltimore, Maryland, 21201, USA

    Barbara S. Bregman

  2. Department of Neurological Surgery and Neuroscience, University of Florida, College of Medicine, Gainesville, Florida, 32610, USA

    Paul J. Reier

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  1. Barbara S. Bregman
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Editors and Affiliations

  1. Max-Planck-Institut für experimentelle Medizin, Hermann-Rein-Str. 3, 3400, Göttingen, Germany

    Hans H. Althaus

  2. Max-Planck-Institut für biophysikalische Chemie, Am Faßberg, 3400, Göttingen-Nikolausberg, Germany

    Wilfried Seifert

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Bregman, B.S., Reier, P.J. (1987). Neural Tissue Transplants Modify Response of the Immature Spinal Cord to Damage. In: Althaus, H.H., Seifert, W. (eds) Glial-Neuronal Communication in Development and Regeneration. NATO ASI Series, vol 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71381-1_31

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  • DOI: https://doi.org/10.1007/978-3-642-71381-1_31

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-71383-5

  • Online ISBN: 978-3-642-71381-1

  • eBook Packages: Springer Book Archive

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