Abstract
Neural tissue transplantation techniques have been used extensively in recent years to examine questions concerning development and regeneration in the developing and mature central nervous system (see 1,2,3, for reviews). For example, transplants derived from various levels of the neuraxis survive, grow, and differentiate when placed into cavities or lesions in the adult or newborn nervous system (4–13). Often anatomical projections between host and transplant tissue are established. In some instances, the transplants are able to mediate recovery of function after CNS lesions either by establishing axonal connections with the host nervous system or by releasing hormones or neurotransmitters which are able to act on neurons within the host (3, 7, 14-19).
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Bregman, B.S., Reier, P.J. (1987). Neural Tissue Transplants Modify Response of the Immature Spinal Cord to Damage. In: Althaus, H.H., Seifert, W. (eds) Glial-Neuronal Communication in Development and Regeneration. NATO ASI Series, vol 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71381-1_31
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