Abstract
Cell interactions must play an essential role in the implementation of the genetic programme. Cell signals during ontogenesis could modulate and, in some cases, determine choices in the processes of cell multiplication, differentiation, maturation, migration, and establishment of connections. This implies that, at molecular levels, the expression of each genetically coded signal molecule, giver (effector) and receiver (receptor), is also modulated by the preceding and the following cell interaction. Thus, in many cases the presence of signal effectors and/or receptors in a given cell should be necessary only for the required time.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Altman, J. (1982). Morphological development of the rat cerebellum and some of its mechanisms. In: The cerebellum, new vistas. Exp. Brain Res. Supp., 6, 8–46.
Barnstable, C. J. (1980). Monoclonal antibodies which recognize different cell types in rat retina. Nature, 286, 231 – 235.
Cuello, A. C., Galfre, G. and Milstein (1979). Detection of substance P in the central nervous system by a monoclonal antibody. Proc. Natl. Acad. Sci. USA, 76, 3532–3536.
Eisenbarth, G. S., Walsh, F. S. and Nirenberg, M. (1979). Monoclonal antibody to a plasma membrane antigen of neurons. Proc. Natl. Acad. Sci. USA, 76, 4913–4917.
Galfre, G., Howe, S., Milstein, C., Butcher, G. and Howard, J. (1977). Antibodies to major histocompatibility antigens produced by hybrid cell lines. Nature, 266, 550–552.
Ghandour, M. S., Langley, O. K. and Clos, J. (1983). Immunohistochemical and biochemical approaches to the development of neuroglia in the CNS, with special reference to cerebellum. Int. J. Devi. Neurosci., 1, 4II–425.
Ghandour, M. S., Foucaud, B. and Gombos, G. (1984). Monoclonal antibodies specific for glial and neuronal antigens in the young rat cerebellum. Neuroscience Lett, 51, 119–125.
Goodman, C. S., Bastiani, M. J., Doe, C. Q., duLAC, S., Helfand, S.L., Kuwada, J. Y. and Thomas, J. B. (1984). Cell recognition during neuronal development. Science, 225, 1271–1279.
Hawkes, R., Niday, E. and Matus, A. (1982). Monoclonal antibodies identify novel neural antigens. Proc. Natl. Acad. Sci. USA, 79, 2410–2414.
Hirn, M., Ghandour, M.S., Deagostini-Bazin, H. and Goridis, C. (1983). Molecular heterogeneity and structural evolution during cerebellar ontogeny detected by monoclonal antibody of the mouse cell surface antigen BSP-2. Brain Res, 265, 87–100.
Kennet, R. H. and Gilbert, F. (1979). Hybrid myelomas producing antibodies against a human neuroblastoma antigen present on fetal brain. Science, 203,1120–1121.
Köhler, G. and Milstein, C. (1975). Continuous cultures of fused cells secreting antibody of predefined specificity. Nature, 356, 495–497.
Köhler, G. and Milstein, G. (1976). Derivation of specific antibody-producing tissue culture and tumour lines by cell fusion. Europ. J. Immunol., 6, 511–519.
Lagenaur, C., Sommer, I. and Schachner, M. (1980). Subclass of astroglia in mouse cerebellum recognized by monoclonal antibody. Develop. Biol., 79, 367–378.
Langley, O. K., Foucaud, B., Ghandour, M. S., de Barry, J., Schladenhaufen, Y. and Gombos, G. (1985). Developmental modified neurone-specific marker in rodent cerebellum. Neuroscience, 14, 147–157.
Mckay, R., Raff, M. C. and Reichardt, L. F. (1981). Monoclonal antibodies to neural antigens. Cold Spring Harbor reports in the Neuroscience, Vol. 2.
Matthew, W. D., Tsavaler, L. L. and Reichardt, L. (1981). Identification of synaptic vesicle specific membrane protein with a wide distribution in neuronal and neurosecretory tissue. J. Cell Biol., 91, 257–269.
Miller, R. H. and Raff, M. C. (1984). Fibrous and protoplasmic astrocytes are biochemically and developmentally distinct. J. Neuroscience, 4, 585–592.
O’farrel, P. H. (1975). High resolution two-dimensional electrophoresis of proteins. J. biol. Chem., 250, 982–986.
Ross, E. M., Reis, D. J. and Joh, T. H. (1981). Monoclonal antibodies to tyrosine hydroxylase: Production and characterization. Brain Res, 208, 493–498.
Schachner, M., Kim, S. K. and Zehnle, R. (1981). Developmental expression in central nervous system of oligodendrocytes cell surface antigens (O antigens) recognized by monoclonal antibodies. Develop. Biol., 83, 328–338.
Sternberger. L. W., Harwell, L. L. and Sternberger, N. (1982). Neurotypy: regional individuality in rat brain detected by immunocytochemistry with monoclonal antibodies. Proc. Natl. Acad. Sci. USA, 79, 1326–1330.
Towbin, H., Staehelin, T. and Gordon, J. (1979). Electrophoretic transfer of proteins from Polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. USA, 76, 4350–4354.
Zipser, B. and Mckay, R. (1981). Monoclonal antibodies distinguish identifiable neurones in the leech. Nature, 289, 549–554.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1987 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Ghandour, M.S., Foucaud, B., Gombos, G. (1987). Developmentally Regulated Glial and Neuronal Antigens Detected by Monoclonal Antibodies. In: Althaus, H.H., Seifert, W. (eds) Glial-Neuronal Communication in Development and Regeneration. NATO ASI Series, vol 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71381-1_10
Download citation
DOI: https://doi.org/10.1007/978-3-642-71381-1_10
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-71383-5
Online ISBN: 978-3-642-71381-1
eBook Packages: Springer Book Archive