Abstract
Beta endorphin is a peptide consisting of 31 amino acids, isolated from the pituitary gland. This peptide is the most potent endogenous opiate. Prolonged pain relief with single intrathecal administration of beta endorphin in cancer patients has been reported by Oyama [1]. But pain relief did not last for more than several days. Many patients with cancer suffer from severe pain for a long period.
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References
Oyama T et al. (1980) Profound analgesic effect of B-endorphin in man. Lancet 1:122–125
Onofrio BM et al. (1981) Continuous low dose intrathecal morphine administration in the treatment of chronic pain of malignant origin. Mayo Clin Proc 56:516–520
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© 1986 Springer-Verlag Berlin Heidelberg
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Jin, T., Murakawa, T., Oyama, T. (1986). Analgesic Effect of Continuous Intrathecal Beta-Endorphin in Cancer Patients. In: Droh, R., Spintge, R. (eds) Closed-Circuit System and Other Innovations in Anaesthesia. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71328-6_30
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DOI: https://doi.org/10.1007/978-3-642-71328-6_30
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-16691-7
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