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Adrenaline Reversal and Postjunctional α-Adrenoceptors

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Abstract

In his seminal paper of 1906, Dale, in describing vasomotor reversal caused by an impure ergot preparation, observed that the pressor response to adrenaline was reversed to a depressor response, but that relaxation of the uterus, also brought about by adrenaline, remained unaltered. Dale concluded that “paralysis of the normally preponderant motor elements allows the emergence of a normally masked inhibitor effect”.

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© 1986 Springer-Verlag Berlin Heidelberg

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Osswald, W., Rodrigues-Pereira, E. (1986). Adrenaline Reversal and Postjunctional α-Adrenoceptors. In: Grobecker, H., Philippu, A., Starke, K. (eds) New Aspects of the Role of Adrenoceptors in the Cardiovascular System. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71313-2_12

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  • DOI: https://doi.org/10.1007/978-3-642-71313-2_12

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-71315-6

  • Online ISBN: 978-3-642-71313-2

  • eBook Packages: Springer Book Archive

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