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Genetic Features of Major Geographical Isolates of Mus musculus

  • K. Moriwaki
  • N. Miyashita
  • H. Suzuki
  • Y. Kurihara
  • H. Yonekawa
Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 127)

Abstract

Laboratory mice have greatly contributed to the remarkable advances in immunogenetics and mammalian molecular genetics for the last decade. At present many different mouse strains, both classical and newly developed, are available for genetic studies. It is quite reasonable with the extensive development of research in this field, that one would like to know the natural origin of laboratory mice based on their genetic constitution. We have already revealed that the mitochondrial genome and most of the nuclear genomes of the present laboratory mice originated from an European subspecies Mus musculus domesticus (Yonekawa et al 1980, 1982; Moriwaki et al 1982, 1985). From mtDNA sequences, Ferris et al (1982) suggested “Common laboratory strains of inbred mice are descended from a single female”. From stand points of either immunogenetics, molecular genetics or evolutionary genetics, it should be desirable to increase further the genetic diversity of the laboratory mice. This could be achieved by utilizing other mouse subspecies. Schwarz and Schwarz (1943) taxonomically discriminated 15 subspecies of mice of Old World origin.

Keywords

Laboratory Mouse EcoRI Fragment Wild Mouse European Subspecies Common Laboratory Strain 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Bonhomme F, Catalan J, Britton-Davidian J, Chapman VM, Moriwaki K, Nevo E, Thaler L (1984) Biochemical diversity and evolution in the genus Mus. Biochem Genet 22:275–303PubMedCrossRefGoogle Scholar
  2. Ferris SD, Sage RD, Wilson AC (1982) Evidence from mtDNA sequences that common laboratory strains of inbred mice are descended from a single female. Nature 295:163–165PubMedCrossRefGoogle Scholar
  3. Ferris SD, Sage RD, Prager EM, Ritte U, Wilson AC (1983) Mitochondrial DNA evolution in mice. Genetics 105:681–721PubMedGoogle Scholar
  4. Hashimoto Y, Suzuki A, Yamakawa T, Wang CH, Bonhomme F, Miyashita N, Moriwaki K (1984) Expression of GM1 and GD1a in liver of wild mice. J Biochem 95:7–12PubMedGoogle Scholar
  5. Kominami R, Mishima Y, Urano Y, Sasaki M, Muramatsu M (1982) Cloning and determination of the transcription termination site of ribosomal RNA gene of the mouse. Nucleic Acid Res 10:1963–1979PubMedCrossRefGoogle Scholar
  6. Kurihara Y, Miyashita N, Moriwaki K, Petras ML, Bonhomme F, Cho WS, Kohno S (1985) Serological survey of T-lymphocyte differentiation antigens in wild mice. Immunogenet 22:211–218CrossRefGoogle Scholar
  7. Minezawa M, Moriwaki K, Kondo K (1981) Geographical survey of protein variations in wild populations of Japanese house mouse, Mus musculus molossinus. Jap J Genet 56:27–39CrossRefGoogle Scholar
  8. Miyashita N, Moriwaki K, Minezawa M, Yonekawa H, Bonhomme F, Migita S, Yu ZC, Lu DY, Cho WS (1985) Allelic constitution of the hemoglobin beta chain in wild population of the house mouse, Mus musculus. Biochem Genet 23:975–986PubMedCrossRefGoogle Scholar
  9. Moriwaki K, Miyashita N, Yonekawa H (1985) Genetic survey of the origin of laboratory mice and its implication in genetic monitoring. In:Archibold J, Ditchfield J, Rowsell HC (eds) The contribution of laboratory animal science to the welfare of man and animals, Gustav Fischer Verlag, Stuttgart, p237Google Scholar
  10. Moriwaki K, Shiroishi T, Minezawa M, Aotsuka T, Kondo K (1979) Frequency distribution of histocompatibility-2 antigenic specificities in the Japanese wild mouse genetically remote from the European subspecies. J Immunogenet 6:99–113PubMedCrossRefGoogle Scholar
  11. Moriwaki K, Shiroishi T, Yonekawa H, Miyashita N, Sagai T (1982) Genetic status of Japanese wild mice and immunological characters of their H-2 antigens. In:Muramatsu T, Cachelin G, Moscona AA, Ikawa Y (eds) Teratocarcinoma and embryonic cell interactions, Japan Scientific Soc Press and Academic Press, Tokyo, pl57Google Scholar
  12. Nei M (1972) Genetic distance between population. Am Natur 106:283–292CrossRefGoogle Scholar
  13. Odaka T, Ikeda H, Yoshikura H, Moriwaki K, Suzuki S (1981) Fv-4:Gene controlling resistance to NB-tropic Friend murine leukemia virus. Distribution in wild mice, introduction into genetic background of BALB/c mice and mapping of chromosomes. J Nat Cancer Inst 67:1123–1127PubMedGoogle Scholar
  14. Robinson PJ, Steinmetz M, Moriwaki K, Fischer-Lindahl K (1984) Beta-2 microglobulin types in mice of wild origin. Immunogenet 20:655–665CrossRefGoogle Scholar
  15. Sage RD (1981) Wild mice. In:Foster HL, Small JD, Fox JG (eds) The mouse in biomedical research, Vol. 1, Academic Press, New York, p39Google Scholar
  16. Schwarz E, Schwarz HK (1943) The wild and commensal stocks of the house mouse. J Mammal 24:59–72CrossRefGoogle Scholar
  17. Suzuki H, Miyashita N, Moriwaki K, Kominami R, Muramatsu M, Kanehisa T, Bonhomme F, Petras ML, Yu ZC, Lu DY (to be published) Evolutionary implication of heterogeneity of the non-transcribed spacer region of ribosomal DNA repeating units in various subspecies of Mus musculus. Mol Biol EvolGoogle Scholar
  18. Yonekawa H, Moriwaki K, Gotoh O, Hayashi JI, Watanabe J, Miyashita N, Petras ML, Tagashira Y (1981) Evolutionary relationship among five subspecies of Mus musculus based on restriction enzyme cleavage patterns of mitochondrial DNA. Genetics 98:801–816PubMedGoogle Scholar
  19. Yonekawa H, Moriwaki K, Gotoh O, Miyashita N, Migita S, Bonhomme F, Hjorth JP, Petras ML, Tagashira Y (1982) Origins of laboratory mice deduced from restriction patterns of mitochondrial DNA. Differentiation 22:222–226PubMedCrossRefGoogle Scholar
  20. Yonekawa H, Moriwaki K, Gotoh O, Watanabe J, Hayashi JI, Miyashita N, Petras ML, Tagashira Y (1980) Relationship between laboratory mice and the subspecies of Mus musculus domesticus based on restriction endonuclease cleavage patterns of mitochondrial DNA. Jap J Genet 50:289–296CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin · Heidelberg 1986

Authors and Affiliations

  • K. Moriwaki
  • N. Miyashita
  • H. Suzuki
  • Y. Kurihara
  • H. Yonekawa

There are no affiliations available

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