Evolution of Immunologically Important Genes in the Genus Mus
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It is somewhat surprising, considering the pre-eminent position the laboratory mouse has held in biological research, how little is known about this species as a whole, with the exception of members of the subgenus Mus, Some of the European and Asian subspecies of Mus have been studied by classical morphologic analysis (Marshall and Sage 1981) and biochemical genetics employing protein polymorphisms (Bonhomme 1978a, 1984; Sage 1981). However, there exists to date very little data at the protein or nucleic acid sequence levels to provide information pertaining to actual patterns of gene evolution or relationships between subspecies or subgenera.
KeywordsImmunoglobulin Heavy Chain Complementarity Determine Region Wild Mouse VK24 Gene Antigen Binding Specificity
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