Effect of Neuroleptics on the Schizophrenic Syndrome

  • H. Y. Meltzer
Conference paper
Part of the Psychopharmacology Series book series (PSYCHOPHARM, volume 3)


Neuroleptics have been the main form of treatment of schizophrenia since their introduction three decades ago. Their use in thousands of clinical studies has pro-vided extensive data with which to evaluate their contribution to the treatment of the schizophrenic syndrome. The evidence for their effectiveness in treating some aspects of the schizophrenic syndrome, e.g., positive symptoms such as delusions and hallucinations, and prevention of relapse and rehospitalization in a large percentage of schizophrenics is unequivocal (Lipton and Burnett 1979). It is also clear that these agents do not completely alleviate delusions and hallucinations in many schizophrenics or have any effect on them in others, and that many aspects of the schizophrenic syndrome, e.g., negative symptoms such as withdrawal, flat affect and avolition are not as effectively treated by neuroleptics as are positive symptoms (Meltzer 1985).


Negative Symptom Schizophrenic Patient Positive Symptom Neuroleptic Drug Neuroleptic Treatment 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1987

Authors and Affiliations

  • H. Y. Meltzer
    • 1
  1. 1.Case Westen Reserve University School of MedicineClevelandUSA

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