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ZAK Zürich pp 258–267Cite as

Wirkungen der Allgemeinanästhetika am ZNS

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Zusammenfassung

Allgemeinanästhetika lösen bekanntlich reversible Bewußtlosigkeit und bei genügend hoher Konzentration am ZNS auch Reaktionslosigkeit gegenüber stärksten Schmerzreizen aus. Diesen als reversibles Koma definierbaren Zustand bezeichnet man gemeinhin als Narkose. Wie Narkose allerdings zustande kommt, ihr Mechanismus also, ist nach wie vor rätselhaft. Einerseits ist unbekannt, wie chemisch inerte Stoffe ohne definierte Struktur-Effekt-Beziehung, für die Rezeptoren als Wirkungsvermittler wohl nicht existieren, überhaupt wirken. Andererseits ist ungeklärt, warum Pharmaka, die die Zellfunktion generell hemmen, in so augenfälliger Weise über eine primäre Funktionsstörung des ZNS die Narkose auslösen.

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Authors
  1. J. O. Arndt
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Editor information

Editors and Affiliations

  1. Institut für Anästhesiologie, Universitätsspital, Rämistraße 100, CH-8091, Zürich, Schweiz

    Georg Hossli

  2. Institut für Anästhesie und Reanimation, Stadtspital Triemli, Birmensdorferstraße 497, CH-8063, Zürich, Schweiz

    Pius Frey

  3. Abteilung für Anästhesie und Reanimation, Kantonsspital Frauenfeld, CH-8500, Frauenfeld, Schweiz

    Georg Kreienbühl

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© 1986 Springer-Verlag Berlin Heidelberg

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Arndt, J.O. (1986). Wirkungen der Allgemeinanästhetika am ZNS. In: Hossli, G., Frey, P., Kreienbühl, G. (eds) ZAK Zürich. Anaesthesiologie und Intensivmedizin / Anaesthesiology and Intensive Care Medicine, vol 188. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71269-2_42

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  • DOI: https://doi.org/10.1007/978-3-642-71269-2_42

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-16618-4

  • Online ISBN: 978-3-642-71269-2

  • eBook Packages: Springer Book Archive

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