Abstract
The “in vitro” activity of lead on adenosine diphosphate (ADP) breakdown and on prostacyclin (PGI2)-like activity has been investigated. The metal reduces ADP clearance and the PGI2 activity promoted by arterial tissue. This effect could be attributed to the inhibition of vessel-wall ectoenzymes, which play an important role in the vascular reactivity.
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© 1986 Springer-Verlag
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Caprino, L., Zenobi, A., Togna, G. (1986). Changes of Vascular Reactivity Induced by Lead. In: Chambers, C.M., Chambers, P.L., Tuomisto, J. (eds) Toxic Interfaces of Neurones, Smoke and Genes. Archives of Toxicology, vol 9. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71248-7_83
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DOI: https://doi.org/10.1007/978-3-642-71248-7_83
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-16589-7
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